Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | POLQ | O75417 | 1/20 | 0.33 |
| ▸ | NCS1 | P62166 | 1/20 | 0.33 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11736358 | 0.88 | KDM4E (0.41) | SMN1; SMN2HSD17B10KDM4ENPSR1ALDH1A1 | |
| SCHEMBL11733170 | 0.87 | TP53 (0.37) | SMN1; SMN2HSD17B10KDM4ENPSR1ALDH1A1 | |
| SCHEMBL11349854 | 0.86 | SMN1; SMN2 (0.37) | SMN1; SMN2HSD17B10KDM4ENPSR1ALDH1A1 | |
| SCHEMBL11729010 | 0.86 | KDM4E (0.43) | SMN1; SMN2HSD17B10KDM4ENPSR1ALDH1A1 | |
| SCHEMBL11734966 | 0.86 | SMN1; SMN2 (0.44) | SMN1; SMN2HSD17B10KDM4ENPSR1ALDH1A1 | |
| SCHEMBL11740117 | 0.86 | TP53 (0.39) | SMN1; SMN2HSD17B10KDM4ENPSR1ALDH1A1 | |
| SCHEMBL11735306 | 0.84 | MAPT (0.39) | SMN1; SMN2HSD17B10KDM4ENPSR1ALDH1A1 | |
| SCHEMBL11736073 | 0.84 | ALDH1A1 (0.38) | SMN1; SMN2HSD17B10KDM4ENPSR1ALDH1A1 | |
| SCHEMBL11741875 | 0.84 | MAPT (0.42) | SMN1; SMN2HSD17B10KDM4ENPSR1ALDH1A1 | |
| SCHEMBL10993418 | 0.83 | MAPT (0.41) | SMN1; SMN2HSD17B10KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4041163-A | N-(5-Tetrazolyl)-4-oxo-4H-pyrimido(2,1-b)benzothiazole-3-carboxamide antiallergy agents | PFIZER INC. (US) | 1977-08-09 | — | — | US | disclosed |