Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | NQO1 | P15559 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | BCR | P11274 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11741259 | 1.00 | ACMSD (0.47) | ACMSDMEN1KMT2AHDAC1HDAC2 | |
| SCHEMBL11735644 | 1.00 | ACMSD (0.47) | ACMSDMEN1KMT2AHDAC1HDAC2 | |
| SCHEMBL2032639 | 0.98 | ACMSD (0.49) | ACMSDMEN1KMT2AHDAC1HDAC2 | |
| SCHEMBL2027405 | 0.91 | ACMSD (0.47) | ACMSDMEN1KMT2AHDAC1HDAC2 | |
| SCHEMBL23466964 | 0.81 | MEN1 (0.54) | ACMSDMEN1KMT2AHDAC1HDAC2 | |
| SCHEMBL10581819 | 0.81 | MEN1 (0.54) | ACMSDMEN1KMT2AHDAC1HDAC2 | |
| SCHEMBL11655788 | 0.81 | MEN1 (0.54) | ACMSDMEN1KMT2AHDAC1HDAC2 | |
| SCHEMBL11655792 | 0.81 | MEN1 (0.54) | ACMSDMEN1KMT2AHDAC1HDAC2 | |
| SCHEMBL10651703 | 0.81 | NPC1 (0.43) | ACMSDMEN1KMT2APSMB5ABL1 | |
| SCHEMBL28161071 | 0.80 | BACE1 (0.42) | ACMSDBACE1NQO1ABL1ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4054582-A | Process for converting cis-hexahydrodibenzo[b,d]pyran-9-ones to trans-hexahydrodibenzo[b,d]-pyran-9-ones | ELI LILLY AND COMPANY (US) | 1977-10-18 | — | — | US | disclosed |