Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 12/20 | 0.57 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.50 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.50 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.42 |
| ▸ | FUCA1 | P04066 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17352352 | 0.81 | EPHX2 (0.58) | GBA1FUCA1 | |
| SCHEMBL15022034 | 0.80 | GBA1 (0.33) | GBA1 | |
| SCHEMBL17718458 | 0.76 | GNAI3 (0.70) | GBA1GNAI3GNAO1GNAI1EPHX1 | |
| SCHEMBL31020849 | 0.76 | GNAI3 (0.70) | GBA1GNAI3GNAO1GNAI1EPHX1 | |
| SCHEMBL4921737 | 0.76 | GNAI3 (0.70) | GBA1GNAI3GNAO1GNAI1EPHX1 | |
| SCHEMBL24210534 | 0.76 | GNAI3 (0.70) | GBA1GNAI3GNAO1GNAI1EPHX1 | |
| SCHEMBL1044920 | 0.76 | GNAI3 (0.70) | GBA1GNAI3GNAO1GNAI1EPHX1 | |
| SCHEMBL9155873 | 0.76 | GNAI3 (0.70) | GBA1GNAI3GNAO1GNAI1EPHX1 | |
| SCHEMBL20746945 | 0.76 | GNAI3 (0.70) | GBA1GNAI3GNAO1GNAI1EPHX1 | |
| SCHEMBL530708 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4048312-A | 2,4-Diaminoquinazolines as antithrombotic agents | ELI LILLY AND COMPANY (US) | 1977-09-13 | — | — | US | disclosed |
| US-3956495-A | 2,4-Diaminoquinazolines as antithrombotic agents | ELI LILLY AND COMPANY (US) | 1976-05-11 | — | — | US | disclosed |