Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL713414 | 0.82 | ESR1 (0.37) | ESR1ESR2 | |
| SCHEMBL28872663 | 0.78 | ESR1 (0.34) | ESR1ESR2 | |
| SCHEMBL28872548 | 0.78 | ESR1 (0.34) | ESR1ESR2 | |
| SCHEMBL28872672 | 0.78 | ESR1 (0.34) | ESR1ESR2 | |
| SCHEMBL11799533 | 0.78 | ESR1 (0.39) | ESR1ESR2 | |
| SCHEMBL25948551 | 0.77 | ADRA2A (0.39) | ESR1ESR2 | |
| SCHEMBL28172890 | 0.77 | ESR1 (0.33) | ESR1ESR2 | |
| SCHEMBL4274025 | 0.75 | ABCB1 (0.35) | ESR1ESR2 | |
| SCHEMBL27959344 | 0.74 | NR1H2 (0.37) | ESR1ESR2 | |
| SCHEMBL121414 | 0.71 | ESR1 (0.42) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4033934-A | ADHESION PROMOTERS | Berger, Abe (US) | 1977-07-05 | — | — | US | disclosed |