Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 2/20 | 0.58 |
| ▸ | TTR | P02766 | 1/20 | 0.53 |
| ▸ | MAPK13 | O15264 | 7/20 | 0.51 |
| ▸ | MAPK12 | P53778 | 7/20 | 0.51 |
| ▸ | MAPK11 | Q15759 | 7/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.51 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.45 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7097760 | 0.84 | MAPK13 (0.61) | TTRMAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL11736669 | 0.84 | NR4A1 (0.53) | AURKAMAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL9629955 | 0.83 | ALDH1A1 (0.54) | MAPK13MAPK12MAPK11MAPK14ALDH1A1 | |
| SCHEMBL7094909 | 0.78 | ALDH1A1 (0.56) | MAPK13MAPK12MAPK11MAPK14ALDH1A1 | |
| SCHEMBL7091072 | 0.76 | KMT2A (0.57) | AURKAMAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL9312496 | 0.76 | TTR (0.73) | TTRPBRM1ALDH1A1KMT2AMEN1 | |
| SCHEMBL11854080 | 0.76 | MAPK13 (0.54) | MAPK13MAPK12MAPK11MAPK14ALDH1A1 | |
| SCHEMBL8012544 | 0.75 | KMT2A (0.57) | MAPK13MAPK12MAPK11MAPK14ALDH1A1 | |
| SCHEMBL27529702 | 0.75 | MAPK14 (0.78) | TTRMAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL1906421 | 0.75 | MAPK14 (0.87) | TTRMAPK13MAPK12MAPK11MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4052398-A | DIAZARHODAMINE-LACTONES, THEIR MANUFACTURE AND THEIR USE AS DYE INTERMEDIATES FOR COPYING PROCESSES | BASF AKTIENGESELLSCHAFT (DT) | 1977-10-04 | — | — | US | disclosed |