Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 3/20 | 0.64 |
| ▸ | MAPK14 | Q16539 | 8/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11826995 | 0.84 | AKR1B1 (0.71) | AKR1B1MAPK14 | |
| SCHEMBL11820581 | 0.82 | AKR1B1 (0.68) | AKR1B1MAPK14 | |
| SCHEMBL11824920 | 0.82 | AKR1B1 (0.64) | AKR1B1MAPK14 | |
| SCHEMBL11824727 | 0.82 | AKR1B1 (0.74) | AKR1B1MAPK14 | |
| SCHEMBL11820546 | 0.81 | AKR1B1 (0.69) | AKR1B1MAPK14 | |
| SCHEMBL11741137 | 0.81 | AKR1B1 (0.49) | AKR1B1MAPK14 | |
| SCHEMBL11824625 | 0.80 | AKR1B1 (0.64) | AKR1B1MAPK14 | |
| SCHEMBL11570176 | 0.80 | AKR1B1 (0.64) | AKR1B1MAPK14 | |
| SCHEMBL11570278 | 0.80 | AKR1B1 (0.64) | AKR1B1MAPK14 | |
| SCHEMBL11827878 | 0.80 | AKR1B1 (0.64) | AKR1B1MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4064141-A | Novel esters of 6,11-dihydrodibenzo-[b.e.]-thiepin-11-one-3-alkanoic acids | SYNTEX (U.S.A.) INC. (US) | 1977-12-20 | — | — | US | claimed |
| US-4064141-A | Novel esters of 6,11-dihydrodibenzo-[b.e.]-thiepin-11-one-3-alkanoic acids | SYNTEX (U.S.A.) INC. (US) | 1977-12-20 | — | — | US | disclosed |