Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 2/20 | 0.64 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11820581 | 0.89 | AKR1B1 (0.68) | AKR1B1MAPK14MAPTKDM4ELMNA | |
| SCHEMBL11826995 | 0.86 | AKR1B1 (0.71) | AKR1B1MAPK14MAPTKDM4ELMNA | |
| SCHEMBL11827878 | 0.86 | AKR1B1 (0.64) | AKR1B1MAPK14KDM4ELMNA | |
| SCHEMBL11570176 | 0.86 | AKR1B1 (0.64) | AKR1B1MAPK14KDM4ELMNA | |
| SCHEMBL11824625 | 0.86 | AKR1B1 (0.64) | AKR1B1MAPK14KDM4ELMNA | |
| SCHEMBL11570278 | 0.86 | AKR1B1 (0.64) | AKR1B1MAPK14KDM4ELMNA | |
| SCHEMBL11820546 | 0.85 | AKR1B1 (0.69) | AKR1B1MAPK14MAPTLMNA | |
| SCHEMBL11824727 | 0.84 | AKR1B1 (0.74) | AKR1B1MAPK14MAPT | |
| SCHEMBL11736784 | 0.82 | AKR1B1 (0.64) | AKR1B1MAPK14 | |
| SCHEMBL11850765 | 0.80 | AKR1B1 (0.61) | AKR1B1MAPK14MAPTKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4000308-A | ANTIINFLAMMATORY, ANALGESICS, ANTIPYREXIA | SYNTEX (U.S.A.) INC. (US) | 1976-12-28 | — | — | US | claimed |
| US-4000308-A | ANTIINFLAMMATORY, ANALGESICS, ANTIPYREXIA | SYNTEX (U.S.A.) INC. (US) | 1976-12-28 | — | — | US | disclosed |
| US-4000288-A | ANALGESICS, ANTIINFLAMMATORY AGENTS, PYREXIA | SYNTEX (U.S.A.) INC. (US) | 1976-12-28 | — | — | US | disclosed |