Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.38 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | P2RY10 | O00398 | 4/20 | 0.34 |
| ▸ | GPR34 | Q9UPC5 | 2/20 | 0.34 |
| ▸ | MVD | P53602 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3446727 | 1.00 | TSHR (0.59) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL374520 | 1.00 | TSHR (0.59) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL3448467 | 1.00 | TSHR (0.59) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL347059 | 1.00 | TSHR (0.59) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL346577 | 1.00 | TSHR (0.59) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL1436153 | 1.00 | TSHR (0.59) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL345682 | 0.98 | TSHR (0.56) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL3447207 | 0.95 | TSHR (0.51) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL19205441 | 0.94 | TSHR (0.56) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL3448299 | 0.94 | TSHR (0.56) | TSHRPOLBAPEX1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6512068-B1 | Substantially transparent adhesive composition for hard tissue, and a method for producing it; the adhesive composition exhibits good adhesiveness to hard tissue, especially to both enamel and dentin, and has the advantage of | KURARAY CO., LTD. (JP) | 2003-01-28 | — | — | US | claimed |
| EP-2853253-B1 | Dental curable composition containing particles with different refractive indexes | SHOFU INC (JP) | 2022-04-27 | — | — | EP | disclosed |
| US-9511005-B2 | Dental curable composition containing particles with different refractive indexes | SHOFU INC. (JP) | 2016-12-06 | — | — | US | disclosed |
| US-9066852-B2 | Dental adhesive primer composition | KABUSHIKI KAISHA SHOFU (JP) | 2015-06-30 | — | — | US | disclosed |
| US-20150094396-A1 | DENTAL CURABLE COMPOSITION CONTAINING PARTICLES WITH DIFFERENT REFRACTIVE INDEXES | SHOFU INC. (JP) | 2015-04-02 | — | — | US | disclosed |
| EP-2853253-A2 | Dental curable composition containing particles with different refractive indexes | Shofu Inc. (JP) | 2015-04-01 | — | — | EP | disclosed |
| US-8389598-B2 | Dental polymerizable composition and kit therefor | SUN MEDICAL CO., LTD. (JP) | 2013-03-05 | — | — | US | disclosed |
| US-20110028589-A1 | DENTAL POLYMERIZABLE COMPOSITION AND KIT THEREFOR | SUN MEDICAL CO., LTD. (JP) | 2011-02-03 | — | — | US | disclosed |
| US-7815434-B2 | Dental coating kit | KURARAY MEDICAL INC. (JP) | 2010-10-19 | — | — | US | disclosed |
| EP-2189147-A1 | DENTAL POLYMERIZABLE COMPOSITION AND KIT THEREFOR | SUN MEDICAL CO., LTD. (JP) | 2010-05-26 | — | — | EP | disclosed |
| EP-1550428-B1 | DENTAL COATING KIT | KURARAY MEDICAL INC (JP) | 2009-03-18 | — | — | EP | disclosed |
| US-7488762-B2 | Two paste-type glass ionomer cement | KABUSHIKI KAISHA SHOFU (JP) | 2009-02-10 | — | — | US | disclosed |
| US-20080182919-A1 | Dental Restorative Composition | SUN MEDICAL CO., LTD. (JP) | 2008-07-31 | — | — | US | disclosed |
| EP-1854447-A1 | DENTAL RESTORATION MATERIAL COMPOSITION | SUN MEDICAL CO., LTD. (JP) | 2007-11-14 | — | — | EP | disclosed |
| US-20060247330-A1 | Two paste-type glass ionomer cement | KABUSHIKI KAISHA SHOFU (JP) | 2006-11-02 | — | — | US | disclosed |
| EP-1057468-B1 | Adhesive composition and method for producing it | KURARAY CO (JP) | 2006-07-19 | — | — | EP | disclosed |
| US-20060078510-A1 | Dental coating kit | KURARAY MEDICAL INC. (JP) | 2006-04-13 | — | — | US | disclosed |
| EP-1550428-A1 | DENTAL COATING KIT | Kuraray Medical Inc. (JP) | 2005-07-06 | — | — | EP | disclosed |
| US-6512068-B1 | Substantially transparent adhesive composition for hard tissue, and a method for producing it; the adhesive composition exhibits good adhesiveness to hard tissue, especially to both enamel and dentin, and has the advantage of | KURARAY CO., LTD. (JP) | 2003-01-28 | — | — | US | disclosed |
| EP-1057468-A1 | Adhesive composition and method for producing it | KURARAY CO., LTD. (JP) | 2000-12-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080182919-A1 | Dental Restorative Composition | PARG, PARN, FHIT | TSHR 3228/4885POLB 269/4885APEX1 1142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.