Sugi Predict

Sugi Predict / Targets / FHIT

FHIT

Bis(5'-adenosyl)-triphosphatase · P49789 · FHIT on Sugi Atlas →

3,740 patent compounds predicted against FHIT, 2,502 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL4709598 SCHEMBL4709598 0.51 7/20
SCHEMBL2569140 SCHEMBL2569140 0.39 6/20
SCHEMBL4711734 SCHEMBL4711734 0.47 5/20
SCHEMBL4759771 SCHEMBL4759771 0.44 5/20
SCHEMBL4712785 SCHEMBL4712785 0.49 3/20
SCHEMBL4758483 SCHEMBL4758483 0.47 3/20
SCHEMBL2470237 SCHEMBL2470237 0.42 3/20
SCHEMBL2470239 SCHEMBL2470239 0.42 3/20
SCHEMBL2470248 SCHEMBL2470248 0.42 3/20
SCHEMBL2470251 SCHEMBL2470251 0.42 3/20
SCHEMBL4710697 SCHEMBL4710697 0.76 2/20
SCHEMBL6109279 SCHEMBL6109279 0.75 2/20
SCHEMBL4710609 SCHEMBL4710609 0.71 2/20
SCHEMBL4710927 SCHEMBL4710927 0.70 2/20
SCHEMBL4708929 SCHEMBL4708929 0.69 2/20
SCHEMBL4708976 SCHEMBL4708976 0.68 2/20
SCHEMBL4390839 SCHEMBL4390839 0.67 2/20
SCHEMBL4709622 SCHEMBL4709622 0.66 2/20
SCHEMBL4711880 SCHEMBL4711880 0.64 2/20
SCHEMBL4709413 SCHEMBL4709413 0.64 2/20

Clinical trials — most relevant to FHIT by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Comparison of Two Different Anesthesia Methods in IVF Procedure PHASE4COMPLETED
Effect of Lithium Carbonate on Postoperative Sleep in Patients Undergoing Videoassisted Thoracic Surgery PHASE4COMPLETED
Comparison of AQUAVAN® Injection to DISOPRIVAN® Injectable Emulsion for Anesthesia During Coronary Artery Surgery PHASE2COMPLETED
Postoperative Delirium in the ICU Setting of an Eastern European Centre nanUNKNOWN
BIS in Critically Ill Patients in ICU nanNOT_YET_RECRUITING
The Influence of Age on EEG Signals and Consciousness During Anesthesia nanCOMPLETED
Development of PK/PD Model for Individualized Propofol Dosing nanCOMPLETED
Recovery From General Anesthesia nanCOMPLETED
Anesthetic Method and Cerebral Outcomes nanUNKNOWN
EEG-based Depth of Anesthesia-monitoring, Effects on Dosage and Cognition nanCOMPLETED
Neurocognitive Disorders After Major Surgery in Elderly nanRECRUITING
Comparing Simplified EEG Monitoring Tool With Standard EEG Monitoring in Patients With Acute Neurological Insult nanUNKNOWN
A Study to Assess Indices of SNAP vs VISTA on Surgical Patients Undergoing General Anesthesia nanCOMPLETED
Efficacy of BIS Monitoring in Deep Hypnotic State nanUNKNOWN
Depth of Anesthesia During Electroconvulsive Therapy nanCOMPLETED
Objective Measurement of Pain in Individuals With Cognitive Deterioration Utilizing Electroencephalography nanCOMPLETED
Bispectral Index Monitoring for Sedation in Elective Colonoscopies of Adult Patients: a Randomized Controlled Trial nanCOMPLETED
Effects of rTMS on Impulsivity and Empathy nanCOMPLETED
BIS Variability and Change in Quality of Recovery After Surgery nanRECRUITING
The Effects of Different General Anesthetics on Serum Folic Acid and Homocysteine Concentrations in Children nanUNKNOWN
Validation of Bispectral Index (BIS)-Monitor in 3 Groups of Newborn Children nanCOMPLETED
The Use of Sedation Score and Bispectral Index for Induction in Geriatric Patients nanCOMPLETED
The Depth of Paediatric Anaesthesia: Observational Trial nanUNKNOWN
Feasibility of Using Depth-of-sedation Measuring Equipment (BIS) to Guide Awake Fibreoptic Intubation nanWITHDRAWN
The Gender Specific Effect on the Results of Ascending Aortic Replacement nanCOMPLETED
Reliability of BIS Monitoring in Neurosurgical Patients nanCOMPLETED
Correlation BIS Scores Mentally Retarded Patients nanCOMPLETED
Electroencephalogram (EEG) in General Anaesthesia - More Than Only a Bispectral Index (BIS) nanCOMPLETED
Assessment of Sedation During Endoscopy nanCOMPLETED
Bilateral Bispectral Index, Asymmetries and Post-operative Delirium nanRECRUITING

Related proteins — ESM-2 sequence neighbours (a FHIT binder may also engage these)

ProteinNameSimilarity
Q1KZG4 — 1.000 Q1KZG4 →
Q9JIX3 — 1.000 Q9JIX3 →
O89106 — 0.999 O89106 →
P49776 — 0.981 P49776 →
Q86KK2 — 0.977 Q86KK2 →
O76463 — 0.971 O76463 →
Q59WG0 — 0.971 Q59WG0 →
O94586 — 0.967 O94586 →
F4KEV7 — 0.966 F4KEV7 →
Q04344 — 0.965 Q04344 →
HSD17B4 Peroxisomal multifunctional enzyme type 2 0.962 landscape →
P62958 — 0.962 P62958 →
P51660 — 0.962 P51660 →
Q8GUN2 — 0.961 Q8GUN2 →
Q5RF69 — 0.961 Q5RF69 →
Q9LDN2 — 0.958 Q9LDN2 →
O07513 — 0.956 O07513 →
A1CGA8 — 0.956 A1CGA8 →
HINT1 Adenosine 5'-monophosphoramidase HINT1 0.956 landscape →
P42856 — 0.956 P42856 →
P17571 — 0.956 P17571 →
P53795 — 0.955 P53795 →
P00908 — 0.955 P00908 →
A0A1L9WLF1 — 0.955 A0A1L9WLF1 →
O93919 — 0.955 O93919 →
O76464 — 0.955 O76464 →
C1H9Q9 — 0.955 C1H9Q9 →
A1DFA8 — 0.955 A1DFA8 →
P25170 — 0.954 P25170 →
P70349 — 0.954 P70349 →