Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER2 | P43116 | 9/20 | 0.48 |
| ▸ | PTGER3 | P43115 | 7/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 5/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PTGFR | P43088 | 3/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.44 |
| ▸ | PTGIR | P43119 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11737423 | 1.00 | PTGER2 (0.48) | PTGER2PTGER3PTGER4HTTPTGFR | |
| SCHEMBL11727007 | 0.91 | PTGER2 (0.49) | PTGER2PTGER3PTGER4HTTPTGFR | |
| SCHEMBL11596612 | 0.87 | PTGER3 (0.59) | PTGER2PTGER3PTGER4HTTPTGFR | |
| SCHEMBL29424280 | 0.87 | PTGER3 (0.59) | PTGER2PTGER3PTGER4HTTPTGFR | |
| SCHEMBL11599710 | 0.87 | PTGER3 (0.59) | PTGER2PTGER3PTGER4HTTPTGFR | |
| SCHEMBL11599718 | 0.87 | PTGER3 (0.59) | PTGER2PTGER3PTGER4HTTPTGFR | |
| SCHEMBL11599713 | 0.87 | PTGER3 (0.59) | PTGER2PTGER3PTGER4HTTPTGFR | |
| SCHEMBL11596602 | 0.87 | PTGER3 (0.59) | PTGER2PTGER3PTGER4HTTPTGFR | |
| SCHEMBL11596606 | 0.87 | PTGER3 (0.59) | PTGER2PTGER3PTGER4HTTPTGFR | |
| SCHEMBL11601571 | 0.87 | PTGER4 (0.37) | PTGER2PTGER3PTGER4HTTPTGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4024181-A | Analogues of prostanoic acids | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-05-17 | — | — | US | claimed |
| US-4024181-A | Analogues of prostanoic acids | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-05-17 | — | — | US | disclosed |