SCHEMBL29424280

SCHEMBL29424280

CCCCC(C)(C)[C@H](O)/C=C/[C@H]1CCC(=O)[C@@H]1C/C=C\CCCC(=O)O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PTGER3 P43115 5/20 0.59
▸ PTGER1 P34995 3/20 0.59
▸ TBXA2R P21731 2/20 0.59
▸ PTGFR P43088 2/20 0.59
▸ PTGER2 P43116 8/20 0.53
▸ PTGER4 P35408 5/20 0.53
▸ HTT P42858 1/20 0.52
▸ PTGIR P43119 2/20 0.48
▸ HPGD P15428 2/20 0.48
▸ NR1I2 O75469 1/20 0.48
▸ ESR1 P03372 1/20 0.48
▸ PGR P06401 1/20 0.48
▸ TSHR P16473 1/20 0.48
▸ MAPK1 P28482 1/20 0.48
▸ OPRK1 P41145 1/20 0.48
▸ PDE4D Q08499 1/20 0.48
▸ TRPA1 O75762 2/20 0.46
▸ ALDH1A1 P00352 2/20 0.46
▸ MEN1 O00255 1/20 0.46
▸ LMNA P02545 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11596606 1.00 PTGER3 (0.59) PTGER3PTGER1TBXA2RPTGFRPTGER2
SCHEMBL11599710 1.00 PTGER3 (0.59) PTGER3PTGER1TBXA2RPTGFRPTGER2
SCHEMBL11596612 1.00 PTGER3 (0.59) PTGER3PTGER1TBXA2RPTGFRPTGER2
SCHEMBL11599718 1.00 PTGER3 (0.59) PTGER3PTGER1TBXA2RPTGFRPTGER2
SCHEMBL11596602 1.00 PTGER3 (0.59) PTGER3PTGER1TBXA2RPTGFRPTGER2
SCHEMBL11599713 1.00 PTGER3 (0.59) PTGER3PTGER1TBXA2RPTGFRPTGER2
SCHEMBL11515062 0.87 PTGER3 (0.48) PTGER3PTGER1TBXA2RPTGFRPTGER2
SCHEMBL11515066 0.87 PTGER3 (0.48) PTGER3PTGER1TBXA2RPTGFRPTGER2
SCHEMBL11737423 0.87 PTGER2 (0.48) PTGER3PTGER1TBXA2RPTGFRPTGER2
SCHEMBL11737415 0.87 PTGER2 (0.48) PTGER3PTGER1TBXA2RPTGFRPTGER2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250333702-A1 CELLS WITH INCREASED IMMUNO-REGULATORY PROPERTIES AND METHODS FOR THEIR USE AND MANUFACTURE THE CHILDREN'S MEDICAL CENTER CORPORATION (US) 2025-10-30 — — US disclosed
US-20250134927-A1 COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING AUTOIMMUNE DISEASES ORCHARD THERAPEUTICS EUROPE LTD (GB) 2025-05-01 — — US disclosed
US-20250101381-A1 CELLS WITH INCREASED IMMUNO-REGULATORY PROPERTIES AND METHODS FOR THEIR USE AND MANUFACTURE THE CHILDREN'S MEDICAL CENTER CORPORATION (US) 2025-03-27 — — US disclosed
CN-113631703-B Using poloxacin viral conduction of amines 瑞威帝基因传递股份有限公司 2025-03-25 — — CN disclosed
US-20240263135-A1 COMPOSITIONS AND METHODS FOR IMMUNE CELL MODULATION IN ADOPTIVE IMMUNOTHERAPIES FATE THERAPEUTICS, INC. 2024-08-08 — — US disclosed
CN-111212648-B Compositions and methods for preventing or treating muscle disorders 莱兰斯坦福初级大学评议会 2024-07-09 — — CN disclosed
CN-112481211-B Cells with increased immunomodulation and methods of use and production thereof 儿童医院公司 2024-07-05 — — CN disclosed
EP-4294919-A1 MAGNETIC SHEAR BIOREACTOR APPARATUS AND METHODS THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2023-12-27 — — EP disclosed
US-11834668-B2 Compounds for improved viral transduction BLUEBIRD BIO, INC. (US) 2023-12-05 — — US disclosed
US-20230313227-A1 COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING HEREDITARY ANGIOEDEMA ORCHARD THERAPEUTICS EUROPE LTD (GB) 2023-10-05 — — US disclosed
US-20230002784-A1 COMPOSITIONS AND METHODS FOR MODIFYING EUKARYOTIC CELLS ORCHARD THERAPEUTICS (EUROPE) LIMITED (GB) 2023-01-05 — — US disclosed
CN-107429232-B Immunoregulatory enhanced cells and methods of use and production thereof 菲特治疗公司 2023-01-03 — — CN disclosed
US-20220370509-A1 COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING CROHN'S DISEASE ORCHARD THERAPEUTICS (EUROPE) LIMITED (GB) 2022-11-24 — — US disclosed
EP-4058043-A1 COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING CROHN'S DISEASE Orchard Therapeutics (Europe) Limited (GB) 2022-09-21 — — EP disclosed
CN-115087455-A Compositions and methods for treating or preventing Crohn's disease 奥查德疗法(欧洲)有限公司 2022-09-20 — — CN disclosed
WO-2022178357-A1 MAGNETIC DESCRIPTION MAGNETIC SHEAR BIOREACTOR APPARATUS AND METHODS THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2022-08-25 — — WO disclosed
CN-114761567-A Compositions and methods for modifying eukaryotic cells 奥查德疗法(欧洲)有限公司 2022-07-15 — — CN disclosed
CN-108220246-B Compounds for improving viral transduction 蓝鸟生物公司 2022-07-12 — — CN disclosed
CN-114561277-A Methods and devices for conditioning cell populations for cell therapy 得克萨斯州大学系统董事会 2022-05-31 — — CN disclosed
EP-3972599-A1 COMBINATION FOR LOWERING SERUM PHOSPHATE IN A PATIENT Ardelyx, Inc. (US) 2022-03-30 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230313227-A1 COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING HEREDITARY ANGIOEDEMA SERPINH1, SERPINB1, SERPINB6 PTGER3 750/4885PTGER1 623/4885TBXA2R 306/4885
US-20250134927-A1 COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING AUTOIMMUNE DISEASES CD4, CD74, HLA-DRB1 PTGER3 1321/4885PTGER1 1381/4885TBXA2R 1062/4885
US-20220370509-A1 COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING CROHN'S DISEASE NOD2, FABP2, TPMT PTGER3 1753/4885PTGER1 1733/4885TBXA2R 3357/4885
US-20230002784-A1 COMPOSITIONS AND METHODS FOR MODIFYING EUKARYOTIC CELLS PHAX, CD4, POLM PTGER3 1197/4885PTGER1 685/4885TBXA2R 3549/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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