Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Linoleic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.63 |
| ▸ | PPARD | Q03181 | 6/20 | 0.63 |
| ▸ | PPARA | Q07869 | 6/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | F7 | P08709 | 5/20 | 0.63 |
| ▸ | F3 | P13726 | 5/20 | 0.63 |
| ▸ | FABP4 | P15090 | 4/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.63 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.63 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.63 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 2/20 | 0.63 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.63 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Linoleic Acid SCHEMBL1173765 | 1.00 | PPARG (0.63) | PPARGPPARDPPARAALDH1A1F7 | |
| Linolenic Acid SCHEMBL1173186 | 0.93 | ALDH1A1 (0.63) | PPARGPPARDPPARAALDH1A1F7 | |
| Linolenic Acid SCHEMBL1173187 | 0.93 | ALDH1A1 (0.63) | PPARGPPARDPPARAALDH1A1F7 | |
| Dodecanoate SCHEMBL17223917 | 0.88 | PRCP (0.56) | PPARGPPARDPPARAALDH1A1FABP4 | |
| Dodecanoate SCHEMBL17223919 | 0.88 | PRCP (0.56) | PPARGPPARDPPARAALDH1A1FABP4 | |
| Linoleic Acid SCHEMBL160683 | 0.81 | PPARG (0.96) | PPARGPPARDPPARAALDH1A1F7 | |
| Linoleic Acid SCHEMBL5874699 | 0.80 | PPARG (0.81) | PPARGPPARDPPARAALDH1A1F7 | |
| Linoleic Acid SCHEMBL25294178 | 0.80 | PPARG (1.00) | PPARGPPARDPPARAALDH1A1F7 | |
| Dihomo-Gamma-Linolenic Acid SCHEMBL20656585 | 0.80 | PPARG (1.00) | PPARGPPARDPPARAALDH1A1F7 | |
| SCHEMBL22498256 | 0.80 | PPARG (1.00) | PPARGPPARDPPARAALDH1A1F7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4661839-A1 | PHYTO-COMPOSITIONS | PHYTOHEAL MEDTECH INTERNATIONAL (AE) | 2025-12-17 | — | — | EP | disclosed |
| WO-2024166055-A1 | \"PHYTO-COMPOSITIONS\ | PHYTOHEAL MEDTECH INTERNATIONAL (AE) | 2024-08-15 | — | — | WO | disclosed |
| US-20230265268-A1 | THERMOPLASTIC ELASTOMER COMPOSITION | POLYMAX THERMOPLASTIC ELASTOMERS, LLC | 2023-08-24 | — | — | US | disclosed |
| EP-3533437-A1 | COMPOSITION CONTAINING LINOLEIC ACID | Sunstar Inc. (JP) | 2019-09-04 | — | — | EP | disclosed |
| US-20190247290-A1 | COMPOSITION CONTAINING LINOLEIC ACID | SUNSTAR INC. (JP) | 2019-08-15 | — | — | US | disclosed |
| EP-2904046-B1 | THERMOPLASTIC ELASTOMER COMPOSITIONS HAVING BIORENEWABLE CONTENT | TEKNOR APEX CO (US) | 2018-11-21 | — | — | EP | disclosed |
| US-10125255-B2 | Thermoplastic elastomer compositions having biorenewable content | TEKNOR APEX COMPANY (US) | 2018-11-13 | — | — | US | disclosed |
| EP-2904045-B1 | THERMOPLASTIC ELASTOMER COMPOSITIONS HAVING BIORENEWABLE CONTENT | TEKNOR APEX CO (US) | 2018-09-19 | — | — | EP | disclosed |
| US-20160376432-A1 | THERMOPLASTIC ELASTOMER COMPOSITIONS HAVING BIORENEWABLE CONTENT | CERESTECH, INC. (CA) | 2016-12-29 | — | — | US | disclosed |
| EP-1256336-B1 | Two-phase gel composition | PENRECO (US) | 2016-10-19 | — | — | EP | disclosed |
| EP-1141111-A1 | GEL COMPOSITIONS | Penreco (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2001007009-A1 | LYSINE OXIDASE LINKAGE OF AGENTS TO TISSUE | PERICOR SCIENCE, INC. (US) | 2001-02-01 | — | — | WO | disclosed |
| WO-2001006829-A2 | LINKAGE OF AGENTS TO TISSUE | PERICOR SCIENCE, INC. (US) | 2001-02-01 | — | — | WO | disclosed |
| WO-2000064408-A1 | WET WIPES HAVING SKIN HEALTH BENEFITS | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2000-11-02 | — | — | WO | disclosed |
| WO-2000026285-A1 | GEL COMPOSITIONS | PENRECO (US) | 2000-05-11 | — | — | WO | disclosed |
| US-6051250-A | STABILIZING AGENT (S) IS/ARE CHOSEN FROM THE GROUP COMPOSED OF GLYCEROL ALGINATES, PROPYLENE GLYCOL ALGINATES, GELLAN GUM AND WELLAN GUM. | L'OREAL (FR) | 2000-04-18 | — | — | US | disclosed |
| US-5866158-A | STORAGE STABILITY | L'OREAL (FR) | 1999-02-02 | — | — | US | disclosed |
| US-5741518-A | Composition composed of an aqueous dispersion of stabilized vesicles of nonionic amphiphilic lipids | L'OREAL (FR) | 1998-04-21 | — | — | US | disclosed |
| US-5626868-A | AMPHOTERIC AND NONIONIC SURFACTANTS WITH LIPID VESICLES | L'OREAL (FR) | 1997-05-06 | — | — | US | disclosed |
| US-5443840-A | Aqueous dispersion phase of lipid vesicles comprising lipid phase containing ionic or nonionic amphiphilic lipid, polyol or isoprenoic acid containing phytyl chain | L'OREAL (FR) | 1995-08-22 | — | — | US | disclosed |