Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | STAT1 | P42224 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | PDXK | O00764 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.32 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.32 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11013147 | 0.75 | PDXK (0.41) | LMNAPDXKALDH1A1KMT2A | |
| SCHEMBL11013377 | 0.72 | PDXK (0.44) | LMNAPDXKALDH1A1KMT2A | |
| SCHEMBL11014520 | 0.69 | CYP1A2 (0.36) | MAPTLMNAPDXKP2RX3ALDH1A1 | |
| SCHEMBL11015245 | 0.65 | PDXK (0.39) | MAPTLMNAPDXKALDH1A1KMT2A | |
| SCHEMBL11017547 | 0.65 | PDXK (0.42) | MAPTLMNAPDXKALDH1A1SMN1; SMN2 | |
| SCHEMBL7542397 | 0.65 | SLC6A2 (0.42) | MAPTLMNACES2CES1ALDH1A1 | |
| Methane SCHEMBL11010980 | 0.65 | PDXK (0.49) | LMNAPDXKP2RX3ALDH1A1KMT2A | |
| SCHEMBL11011837 | 0.64 | KDM4E (0.57) | MAPTLMNAPDXKP2RX3ALDH1A1 | |
| SCHEMBL11011501 | 0.63 | PDXK (0.35) | MAPTLMNAPDXKALDH1A1SMN1; SMN2 | |
| SCHEMBL8445181 | 0.62 | CES1 (0.60) | MAPTLMNACES2CES1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4053606-A | ANTIINFLAMMATORY AND ANTIARTHRITIC AGENTS | MERCK & CO., INC. (US) | 1977-10-11 | — | — | US | disclosed |