Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 11/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.78 |
| ▸ | NPC1 | O15118 | 8/20 | 0.78 |
| ▸ | IDO1 | P14902 | 2/20 | 0.73 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.71 |
| ▸ | RAB9A | P51151 | 8/20 | 0.67 |
| ▸ | KLF5 | Q13887 | 3/20 | 0.67 |
| ▸ | POLB | P06746 | 2/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | HTT | P42858 | 2/20 | 0.66 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | GAA | P10253 | 1/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.66 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.66 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.66 |
| ▸ | MITF | O75030 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12868876 | 1.00 | MEN1 (0.78) | MEN1KMT2ANPC1IDO1PAX8 | |
| SCHEMBL29364291 | 1.00 | MEN1 (0.78) | MEN1KMT2ANPC1IDO1PAX8 | |
| SCHEMBL1173951 | 1.00 | MEN1 (0.78) | MEN1KMT2ANPC1IDO1PAX8 | |
| SCHEMBL12868819 | 0.88 | MEN1 (0.81) | MEN1KMT2ANPC1IDO1PAX8 | |
| SCHEMBL2847708 | 0.87 | MEN1 (0.85) | MEN1KMT2ANPC1IDO1PAX8 | |
| SCHEMBL683715 | 0.87 | MEN1 (0.85) | MEN1KMT2ANPC1IDO1PAX8 | |
| SCHEMBL12868862 | 0.86 | ESRRG (0.60) | MEN1KMT2ANPC1IDO1PAX8 | |
| SCHEMBL1175043 | 0.86 | ESRRG (0.60) | MEN1KMT2ANPC1IDO1PAX8 | |
| SCHEMBL1175041 | 0.86 | ESRRG (0.60) | MEN1KMT2ANPC1IDO1PAX8 | |
| SCHEMBL14223812 | 0.85 | MEN1 (0.81) | MEN1KMT2ANPC1IDO1PAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110046101-A1 | BATE-LACTAMASE INHIBITORS | DMITRIENKO GARY I | 2011-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110046101-A1 | BATE-LACTAMASE INHIBITORS | OXA1L, MGAM, PREP | MEN1 1096/4885KMT2A 1901/4885NPC1 1829/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.