Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 11/20 | 0.85 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.85 |
| ▸ | NPC1 | O15118 | 7/20 | 0.85 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.81 |
| ▸ | RAB9A | P51151 | 7/20 | 0.76 |
| ▸ | RRM1 | P23921 | 4/20 | 0.76 |
| ▸ | KLF5 | Q13887 | 3/20 | 0.76 |
| ▸ | IDO1 | P14902 | 2/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.71 |
| ▸ | MAPT | P10636 | 3/20 | 0.71 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.71 |
| ▸ | HTT | P42858 | 2/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.71 |
| ▸ | GAA | P10253 | 1/20 | 0.71 |
| ▸ | HPGD | P15428 | 1/20 | 0.71 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.71 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.71 |
| ▸ | POLB | P06746 | 2/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL683715 | 1.00 | MEN1 (0.85) | MEN1KMT2ANPC1PAX8RAB9A | |
| SCHEMBL29414666 | 0.90 | PAX8 (1.00) | MEN1KMT2ANPC1PAX8RAB9A | |
| SCHEMBL800974 | 0.90 | PAX8 (1.00) | MEN1KMT2ANPC1PAX8RAB9A | |
| SCHEMBL16713131 | 0.90 | PAX8 (1.00) | MEN1KMT2ANPC1PAX8RAB9A | |
| SCHEMBL14223812 | 0.90 | MEN1 (0.81) | MEN1KMT2ANPC1PAX8RAB9A | |
| SCHEMBL12868819 | 0.90 | MEN1 (0.81) | MEN1KMT2ANPC1PAX8RAB9A | |
| SCHEMBL1679411 | 0.90 | PAX8 (1.00) | MEN1KMT2ANPC1PAX8RAB9A | |
| SCHEMBL14906922 | 0.89 | MEN1 (0.81) | MEN1KMT2ANPC1PAX8RAB9A | |
| SCHEMBL16035633 | 0.89 | MEN1 (0.81) | MEN1KMT2ANPC1PAX8RAB9A | |
| SCHEMBL21211326 | 0.88 | MEN1 (0.75) | MEN1KMT2ANPC1PAX8RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100130450-A1 | Methods of Treating Fungal Infections | NORTHEASTERN UNIVERSITY (US) | 2010-05-27 | — | — | US | disclosed |
| EP-2146702-A2 | METHODS OF TREATING FUNGAL INFECTIONS | NorthEastern University (US) | 2010-01-27 | — | — | EP | disclosed |
| WO-2008137128-A2 | METHODS OF TREATING FUNGAL INFECTIONS | NORTHEASTERN UNIVERSITY (US) | 2008-11-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100130450-A1 | Methods of Treating Fungal Infections | ERG28, DPM1, COXFA4L2 | MEN1 1822/4885KMT2A 4135/4885NPC1 904/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.