Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | UTS2R | Q9UKP6 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11738728 | 0.93 | HRH3 (0.42) | HRH3NPC1RAB9AKMT2AKDM4E | |
| SCHEMBL11742440 | 0.89 | SIGMAR1 (0.41) | HRH3NPC1RAB9AKMT2AKDM4E | |
| SCHEMBL11743478 | 0.86 | NPC1 (0.38) | NPC1RAB9AKMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL11743857 | 0.86 | NPC1 (0.38) | NPC1RAB9AKMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL11738748 | 0.86 | NPC1 (0.38) | NPC1RAB9AKMT2AKDM4ESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11746962 | 0.85 | NPC1 (0.37) | NPC1RAB9AKMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL11736431 | 0.84 | NPC1 (0.37) | NPC1RAB9AKMT2AKDM4ELMNA | |
| SCHEMBL11737961 | 0.84 | NPC1 (0.37) | NPC1RAB9AKMT2AKDM4ELMNA | |
| Hydrochloric Acid SCHEMBL11741645 | 0.83 | NPC1 (0.42) | NPC1RAB9AKMT2AKDM4EMAPT | |
| SCHEMBL11740038 | 0.83 | NPC1 (0.39) | NPC1RAB9AKMT2AKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4033977-A | ANTIINFLAMMATORY, ANTIDEPRESSANT | AMERICAN HOME PRODUCTS CORPORATION (US) | 1977-07-05 | — | — | US | claimed |