Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ARG1 | P05089 | 1/20 | 0.41 |
| ▸ | ARG2 | P78540 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27033191 | 1.00 | CYP1A2 (0.55) | CYP1A2MAPK1SMN1; SMN2LMNATSHR | |
| SCHEMBL5619843 | 0.92 | CYP1A2 (0.64) | CYP1A2MAPK1SMN1; SMN2LMNATSHR | |
| Hydrochloric Acid SCHEMBL11679803 | 0.90 | CYP1A2 (0.62) | CYP1A2MAPK1SMN1; SMN2LMNATSHR | |
| Bromide SCHEMBL11328785 | 0.90 | CYP1A2 (0.62) | CYP1A2MAPK1SMN1; SMN2LMNATSHR | |
| SCHEMBL11668210 | 0.89 | CYP1A2 (0.47) | CYP1A2MAPK1SMN1; SMN2LMNATSHR | |
| SCHEMBL8381328 | 0.86 | CYP1A2 (0.65) | CYP1A2MAPK1SMN1; SMN2LMNATSHR | |
| SCHEMBL30701355 | 0.85 | L3MBTL1 (0.47) | CYP1A2MAPK1SMN1; SMN2PAOXKMT2A | |
| SCHEMBL4381054 | 0.84 | GLA (0.55) | CYP1A2MAPK1SMN1; SMN2LMNAMEN1 | |
| Sebacic Acid SCHEMBL4458306 | 0.84 | CYP1A2 (0.63) | CYP1A2MAPK1SMN1; SMN2LMNATSHR | |
| SCHEMBL26180910 | 0.83 | CYP1A2 (0.68) | CYP1A2MAPK1SMN1; SMN2LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4049653-A | ANALGESICS, ANTIANXIETY AGENTS | ABBOTT LABORATORIES (US) | 1977-09-20 | — | — | US | disclosed |
| US-4025630-A | Anesthesia methods using benzopyrans and esters thereof as pre-anesthesia medication | ABBOTT LABORATORIES (US) | 1977-05-24 | — | — | US | disclosed |
| US-3941782-A | Heterocyclic esters of benzopyrans | SHARPS ASSOCIATES (US) | 1976-03-02 | — | — | US | disclosed |