Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | DGKA | P23743 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PAM | P19021 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 3/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL245031 | 0.93 | TSHR (0.54) | TSHRDGKACES2CES1LMNA | |
| SCHEMBL248383 | 0.93 | TSHR (0.54) | TSHRDGKACES2CES1LMNA | |
| SCHEMBL20471383 | 0.93 | TSHR (0.54) | TSHRDGKACES2CES1LMNA | |
| SCHEMBL93600 | 0.87 | — | — | |
| Ethylene SCHEMBL624958 | 0.85 | TSHR (0.53) | TSHRDGKAMIFCES2CES1 | |
| SCHEMBL11791452 | 0.83 | TSHR (0.61) | TSHRDGKACES2CES1LMNA | |
| SCHEMBL5922618 | 0.83 | TSHR (0.52) | TSHRDGKAMIFCES2CES1 | |
| Alcohol SCHEMBL21049663 | 0.83 | TSHR (0.52) | TSHRDGKACES2CES1HPGD | |
| SCHEMBL8736138 | 0.82 | TSHR (0.33) | TSHRALDH1A1 | |
| Vinyl Chloride SCHEMBL8507026 | 0.82 | TSHR (0.50) | TSHRDGKAMIFCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4057619-A | Ocular therapeutic system with selected membranes for administering ophthalmic drug | ALZA CORPORATION (US) | 1977-11-08 | — | — | US | disclosed |