Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | USP5 | P45974 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8688169 | 0.88 | KMT2A (0.53) | KMT2AUSP5NR4A2SLC22A12ALDH1A1 | |
| SCHEMBL11733812 | 0.88 | KMT2A (0.53) | KMT2AUSP5NR4A2ALDH1A1CYP2C19 | |
| SCHEMBL5629846 | 0.79 | TTR (0.52) | ALDH1A1TSHR | |
| SCHEMBL11743403 | 0.77 | NR4A2 (0.52) | KMT2AUSP5NR4A2ALDH1A1CYP2C19 | |
| SCHEMBL11089924 | 0.77 | USP5 (0.49) | KMT2AUSP5NR4A2SLC22A12ALDH1A1 | |
| SCHEMBL11736603 | 0.77 | KMT2A (0.49) | KMT2AUSP5NR4A2SLC22A12ALDH1A1 | |
| SCHEMBL11741738 | 0.75 | TTR (0.57) | KMT2AUSP5NR4A2ALDH1A1CYP2C19 | |
| SCHEMBL3626525 | 0.75 | TTR (0.57) | KMT2AUSP5NR4A2ALDH1A1CYP2C19 | |
| SCHEMBL5375163 | 0.75 | NR4A2 (0.54) | KMT2AUSP5NR4A2ALDH1A1CYP2C19 | |
| SCHEMBL11743022 | 0.75 | USP5 (0.46) | KMT2AUSP5NR4A2SLC22A12ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4052395-A | AGRICULTURAL FUNGICIDAL COMPOSITIONS CONTAINING 6-(SUBSTITUTED PHENYL)-PYRIDAZINONES AND SAID PYRIDAZINONES | SANKYO COMPANY LIMITED (JA) | 1977-10-04 | — | — | US | disclosed |