Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | ACACA | Q13085 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | PTGFR | P43088 | 1/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KDM4A | O75164 | 1/20 | 0.34 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.34 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.33 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11787985 | 0.87 | FFAR4 (0.48) | FFAR4FFAR1ACACBACACAALOX5 | |
| SCHEMBL11795156 | 0.84 | FFAR4 (0.46) | FFAR4FFAR1ACACBACACATBXA2R | |
| SCHEMBL11791276 | 0.82 | FFAR4 (0.69) | FFAR4FFAR1TBXA2RPTGFRPTGER2 | |
| SCHEMBL11791279 | 0.82 | FFAR4 (0.69) | FFAR4FFAR1TBXA2RPTGFRPTGER2 | |
| SCHEMBL11791284 | 0.82 | FFAR4 (0.69) | FFAR4FFAR1TBXA2RPTGFRPTGER2 | |
| SCHEMBL11603782 | 0.81 | FFAR4 (0.47) | FFAR4FFAR1ACACBACACAALOX5 | |
| SCHEMBL11793752 | 0.81 | FFAR4 (0.43) | FFAR4FFAR1ACACBACACAALOX5 | |
| SCHEMBL11742346 | 0.80 | FFAR4 (0.47) | FFAR4FFAR1ACACBACACAALOX5 | |
| SCHEMBL11792939 | 0.77 | MAPT (0.50) | FFAR4FFAR1TBXA2RPTGFRPTGER2 | |
| SCHEMBL11795088 | 0.75 | FFAR4 (0.65) | FFAR4FFAR1TBXA2RPTGFRPTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3989749-A | RENAL VASODILATORS, ANTITHROMBUS | MERCK & CO., INC. (US) | 1976-11-02 | — | — | US | disclosed |