Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11743442 | 0.89 | MAPT (0.51) | MAPTALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL14996180 | 0.86 | KMT2A (0.67) | MAPTALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL14996182 | 0.85 | MAPT (0.69) | MAPTALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL3504748 | 0.78 | KMT2A (0.58) | MAPTALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL30133462 | 0.78 | KMT2A (0.58) | MAPTALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL11743606 | 0.78 | KMT2A (0.58) | MAPTALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL11746541 | 0.78 | PDE4D (0.70) | MAPTALDH1A1KMT2ANPC1LMNA | |
| SCHEMBL13059438 | 0.76 | KMT2A (0.68) | MAPTALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL22782402 | 0.75 | MAPT (0.66) | MAPTALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL22196923 | 0.74 | KMT2A (0.66) | MAPTALDH1A1SMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4013663-A | BETA-RECEPTOR BLOCKING AGENTS | KNOLL A.G. CHEMISCHE FABRIKEN (DT) | 1977-03-22 | — | — | US | disclosed |