Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | GLA | P06280 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.56 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14996180 | 0.93 | KMT2A (0.67) | MAPTLMNAKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL22782402 | 0.90 | MAPT (0.66) | MAPTLMNAKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL22782306 | 0.88 | MAPT (0.70) | MAPTLMNAKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL21256062 | 0.87 | MAPT (0.62) | MAPTLMNAKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL22782305 | 0.86 | MAPT (0.61) | MAPTLMNAKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL30133462 | 0.85 | KMT2A (0.58) | MAPTLMNAKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL3504748 | 0.85 | KMT2A (0.58) | MAPTLMNAKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL11743606 | 0.85 | KMT2A (0.58) | MAPTLMNAKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL11742452 | 0.85 | MAPT (0.54) | MAPTLMNAKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL13059438 | 0.82 | KMT2A (0.68) | MAPTLMNAKMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8455479-B2 | Heterocyclic compounds | PANACEA BIOTEC LIMITED (IN) | 2013-06-04 | — | — | US | disclosed |