SCHEMBL11744397

SCHEMBL11744397

CCC(Cc1ccccc1)C(=O)C(=NO)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.53
PPARG P37231 3/20 0.45
CPA1 P15085 4/20 0.44
CPA3 P15088 3/20 0.44
FOLH1 Q04609 1/20 0.44
CPB1 P15086 1/20 0.44
CPB2 Q96IY4 1/20 0.44
PPARD Q03181 1/20 0.42
PPARA Q07869 1/20 0.42
LTA4H P09960 2/20 0.41
MME P08473 1/20 0.41
EPHX2 P34913 1/20 0.41
CTBP2 P56545 1/20 0.41
SLC1A3 P43003 1/20 0.41
SLC1A2 P43004 1/20 0.41
SLC1A1 P43005 1/20 0.41
TRPA1 O75762 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL620307 0.83 CYP1A2 (0.64) CYP1A2PPARGCPA1CPA3FOLH1
SCHEMBL11743875 0.82 GRIK1 (0.46) EPHX2
Acetamide SCHEMBL7277641 0.78 CYP1A2 (0.56) CYP1A2PPARGCPA1CPA3FOLH1
SCHEMBL265514 0.76 CYP1A2 (0.83) CYP1A2PPARGCPA1CPA3FOLH1
SCHEMBL491524 0.76 CYP1A2 (0.83) CYP1A2PPARGCPA1CPA3FOLH1
SCHEMBL265063 0.76 CYP1A2 (0.83) CYP1A2PPARGCPA1CPA3FOLH1
SCHEMBL4886609 0.76 CYP1A2 (0.69) CYP1A2PPARGCPA1CPA3FOLH1
SCHEMBL10608715 0.75 CYP1A2 (0.52) CYP1A2PPARGCPA1CPA3FOLH1
SCHEMBL10608708 0.75 CYP1A2 (0.52) CYP1A2PPARGCPA1CPA3FOLH1
SCHEMBL21895912 0.74 CYP1A2 (0.67) CYP1A2PPARGCPA1CPA3FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4042596-A 2-Alkyl-5-phenethyl-4-oxazolecarboxylic acids and derivatives SANDOZ, INC. (US) 1977-08-16 US disclosed