SCHEMBL620307

SCHEMBL620307

CCC(Cc1ccccc1)C(=O)C(=O)O

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.64
CPA1 P15085 6/20 0.52
CPA3 P15088 3/20 0.52
FOLH1 Q04609 2/20 0.52
CPB1 P15086 1/20 0.52
CPB2 Q96IY4 1/20 0.52
PPARG P37231 3/20 0.51
PPARD Q03181 1/20 0.48
PPARA Q07869 1/20 0.48
SLC1A3 P43003 1/20 0.47
SLC1A2 P43004 1/20 0.47
SLC1A1 P43005 1/20 0.47
TRPA1 O75762 1/20 0.47
EPHX2 P34913 1/20 0.47
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
ALPI P09923 1/20 0.46
PKM P14618 1/20 0.46
PTGS1 P23219 1/20 0.46
XIAP P98170 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetamide SCHEMBL7277641 0.93 CYP1A2 (0.56) CYP1A2CPA1CPA3FOLH1CPB1
SCHEMBL7330810 0.85 PPARG (0.60) CYP1A2CPA1PPARGPPARDPPARA
SCHEMBL265063 0.84 CYP1A2 (0.83) CYP1A2CPA1CPA3FOLH1CPB1
SCHEMBL491524 0.84 CYP1A2 (0.83) CYP1A2CPA1CPA3FOLH1CPB1
SCHEMBL265514 0.84 CYP1A2 (0.83) CYP1A2CPA1CPA3FOLH1CPB1
SCHEMBL4886609 0.84 CYP1A2 (0.69) CYP1A2CPA1CPA3FOLH1CPB1
SCHEMBL7333189 0.84 PPARG (0.49) CYP1A2CPA1PPARGPPARDPPARA
SCHEMBL9577446 0.84 PPARG (0.56) CYP1A2PPARGPPARDPPARAEPHX2
SCHEMBL11744397 0.83 CYP1A2 (0.53) CYP1A2CPA1CPA3FOLH1CPB1
SCHEMBL6722161 0.82 CYP1A2 (0.67) CYP1A2CPA1CPA3FOLH1CPB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1437401-B1 Oxidoreductase IEP GMBH (DE) 2010-12-15 EP claimed
EP-1685248-B1 OXIDOREDUCTASE FROM METSCHNIKOWIA ZOBELLII IEP GMBH (DE) 2010-06-09 EP claimed
EP-2123760-A1 Enzymatic method for enantioselective reduction of keto compounds IEP GmbH (DE) 2009-11-25 EP claimed
EP-1383899-B1 ENZYMATIC METHOD FOR THE ENANTIOSELECTIVE REDUCTION OF KETO COMPOUNDS IEP GMBH (DE) 2009-09-23 EP claimed
EP-1762625-B1 Reductase gene and use thereof SUMITOMO CHEMICAL CO (JP) 2009-07-15 EP claimed
US-20080233619-A1 Process For the Enantioselective Enzymatic Reduction of Keto Compounds IEP GMBH (DE) 2008-09-25 US claimed
CN-101273136-A Process for enantioselective enzymatic reduction of keto compounds IEP GMBH (DE) 2008-09-24 CN claimed
EP-1437401-A1 Oxidoreductase Juelich Enzyme Products GmbH (DE) 2004-07-14 EP claimed
EP-1383899-A2 ENZYMATIC METHOD FOR THE ENANTIOSELECTIVE REDUCTION OF KETO COMPOUNDS Jülich Enzyme Products GmbH (DE) 2004-01-28 EP claimed
WO-2002086126-A2 ENZYMATIC METHOD FOR THE ENANTIOSELECTIVE REDUCTION OF KETO COMPOUNDS JUELICH ENZYME PRODUCTS GMBH (DE) 2002-10-31 WO claimed
US-20250275560-A1 PROCESS OF MAKING GINGEROL COMPOUNDS AND THEIR USE AS FLAVOR MODIFIERS FIRMENICH SA (CH) 2025-09-04 US disclosed
CN-119177259-B Method for synthesizing optically active (R) -2-hydroxy-4-phenylbutyric acid by utilizing multienzyme catalysis in micro-flow field 南京工业大学 2025-03-14 CN disclosed
CN-119177259-A Method for synthesizing optically active (R) -2-hydroxy-4-phenylbutyric acid by utilizing multienzyme catalysis in micro-flow field 南京工业大学 2024-12-24 CN disclosed
EP-4307919-A2 PROCESS OF MAKING GINGEROL COMPOUNDS AND THEIR USE AS FLAVOR MODIFIERS Firmenich SA (CH) 2024-01-24 EP disclosed
EP-2403953-B1 METHOD FOR STEREOSELECTIVE ENZYMATIC REDUCTION OF KETO COMPOUNDS CAMBREX IEP GMBH (DE) 2017-05-10 EP disclosed
US-4460579-A HYPOTENSIVE AGENTS, ANGIOTENSIN CONVERTING ENZYME INHIBITORS E. R. SQUIBB & SONS, INC. (US) 1984-07-17 US disclosed
EP-0080822-A1 Anti-hypertensive prolinol-based peptides BEECHAM GROUP PLC (GB) 1983-06-08 EP disclosed
EP-0054862-A1 Substituted dipeptides, processes for their preparation and pharmaceutical compositions containing them and their use in the inhibition of enkephalinase SCHERING CORPORATION (US) 1982-06-30 EP disclosed
EP-0049506-A1 N-carboxyalkyl dipeptides, a process for preparing and a pharmaceutical composition comprising the same MERCK & CO. INC. (US) 1982-04-14 EP disclosed
EP-0046289-A2 Substituted enantholactam derivatives as antihypertensives, a process for preparing and a pharmaceutical composition containing them, and intermediates MERCK & CO. INC. (US) 1982-02-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250275560-A1 PROCESS OF MAKING GINGEROL COMPOUNDS AND THEIR USE AS FLAVOR MODIFIERS GMPS, UMPS, IMPDH1 CYP1A2 4282/4885CPA1 4225/4885CPA3 4198/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.