Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS2 | Q9H2K2 | 12/20 | 0.72 |
| ▸ | PARP2 | Q9UGN5 | 11/20 | 0.72 |
| ▸ | PARP15 | Q460N3 | 11/20 | 0.72 |
| ▸ | PARP10 | Q53GL7 | 10/20 | 0.72 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.61 |
| ▸ | TNKS | O95271 | 1/20 | 0.57 |
| ▸ | PARP1 | P09874 | 1/20 | 0.57 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.57 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.57 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11750178 | 0.84 | TNKS2 (1.00) | TNKS2PARP2PARP15PARP10PARP14 | |
| SCHEMBL25324784 | 0.78 | TNKS2 (1.00) | TNKS2PARP2PARP15PARP10PARP14 | |
| SCHEMBL25324487 | 0.76 | PARP2 (1.00) | TNKS2PARP2PARP15PARP10PARP14 | |
| SCHEMBL11222988 | 0.73 | HSD17B10 (0.56) | HSD17B10PDE11ATP53MAPTPOLB | |
| SCHEMBL25324223 | 0.72 | TNKS2 (1.00) | TNKS2PARP2PARP15PARP10PARP14 | |
| SCHEMBL25326183 | 0.72 | TNKS2 (1.00) | TNKS2PARP2PARP15PARP10PARP14 | |
| SCHEMBL11011832 | 0.70 | MAPT (0.69) | TP53MAPTKDM4EPOLBSMN1; SMN2 | |
| SCHEMBL31338680 | 0.70 | MAPT (0.66) | TP53MAPTKDM4EPOLBSMN1; SMN2 | |
| SCHEMBL25324791 | 0.70 | TNKS2 (0.78) | TNKS2PARP2PARP15PARP10PARP14 | |
| SCHEMBL11748893 | 0.69 | TNKS2 (0.66) | TNKS2PARP2PARP15PARP10PARP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4064261-A | TRIAZOLOBENOXAZOLE, TRIAZOLOBENZOTHIAZOLE COMPOUNDS | ELI LILLY AND COMPANY (US) | 1977-12-20 | — | — | US | disclosed |