SCHEMBL11745263

SCHEMBL11745263

CCOC(=O)C(CC(=O)OCC(C)O)P(=O)(OCC)OCC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.43
TSHR P16473 2/20 0.43
MAPT P10636 1/20 0.41
CYP3A4 P08684 3/20 0.37
ALOX15 P16050 2/20 0.37
TDP1 Q9NUW8 1/20 0.37
GAA P10253 2/20 0.35
POLB P06746 2/20 0.33
CHRM1 P11229 1/20 0.33
ADORA1 P30542 1/20 0.33
HSD17B10 Q99714 1/20 0.33
LPAR6 P43657 1/20 0.32
LPAR1 Q92633 1/20 0.32
LPAR4 Q99677 1/20 0.32
LPAR5 Q9H1C0 1/20 0.32
LPAR2 Q9HBW0 1/20 0.32
LPAR3 Q9UBY5 1/20 0.32
ENPP2 Q13822 1/20 0.32
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9461450 0.87 ALDH1A1 (0.54) ALDH1A1TSHRMAPTCYP3A4ALOX15
SCHEMBL11690303 0.85 ALDH1A1 (0.53) ALDH1A1TSHRMAPTCYP3A4ALOX15
SCHEMBL11747273 0.82 LPAR1 (0.42) ALDH1A1TSHRLPAR6LPAR1LPAR4
SCHEMBL11744826 0.80 ALDH1A1 (0.44) ALDH1A1TSHRMAPTCYP3A4ALOX15
SCHEMBL28041407 0.79 ALDH1A1 (0.43) ALDH1A1TSHRMAPTCYP3A4ALOX15
SCHEMBL7216304 0.77 ALDH1A1 (0.43) ALDH1A1TSHRMAPTCYP3A4ALOX15
SCHEMBL1984906 0.77 ALDH1A1 (0.41) ALDH1A1TSHRMAPTCYP3A4ALOX15
SCHEMBL17397291 0.76 ALDH1A1 (0.45) ALDH1A1TSHRMAPTCYP3A4ALOX15
SCHEMBL30459970 0.76 ALDH1A1 (0.49) ALDH1A1TSHRMAPTCYP3A4ALOX15
SCHEMBL11744447 0.75 ALDH1A1 (0.41) ALDH1A1TSHRMAPTCYP3A4ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4062829-A PHOSPHORUS CONTAINING DICARBOXYLIC ACID ESTERS EMERY INDUSTRIES, INC. (US) 1977-12-13 US claimed
US-4062829-A PHOSPHORUS CONTAINING DICARBOXYLIC ACID ESTERS EMERY INDUSTRIES, INC. (US) 1977-12-13 US disclosed