Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | GRK2 | P25098 | 1/20 | 0.59 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 3/20 | 0.54 |
| ▸ | CA1 | P00915 | 3/20 | 0.54 |
| ▸ | CA2 | P00918 | 3/20 | 0.54 |
| ▸ | CA4 | P22748 | 3/20 | 0.54 |
| ▸ | CA7 | P43166 | 3/20 | 0.54 |
| ▸ | CA9 | Q16790 | 3/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.54 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.54 |
| ▸ | CA6 | P23280 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 5/20 | 0.48 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.48 |
| ▸ | CA5A | P35218 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11748147 | 0.90 | NOTUM (0.61) | TSHRPOLBKMT2AGRK2CTDSP1 | |
| SCHEMBL20676025 | 0.82 | CA12 (0.74) | TSHRPOLBKMT2AGRK2CTDSP1 | |
| SCHEMBL1008592 | 0.81 | SMN1; SMN2 (0.60) | TSHRPOLBKMT2AGRK2CTDSP1 | |
| SCHEMBL5841909 | 0.80 | RECQL (0.62) | TSHRPOLBKMT2AGRK2CTDSP1 | |
| SCHEMBL21121486 | 0.79 | TSHR (0.57) | TSHRPOLBKMT2AGRK2CTDSP1 | |
| Hydrochloric Acid SCHEMBL11747023 | 0.79 | RECQL (0.61) | TSHRPOLBKMT2AGRK2CTDSP1 | |
| SCHEMBL2221436 | 0.78 | TSHR (0.71) | TSHRPOLBKMT2AGRK2CTDSP1 | |
| SCHEMBL23067586 | 0.77 | CA12 (0.57) | TSHRPOLBKMT2AGRK2CTDSP1 | |
| SCHEMBL7825178 | 0.77 | TSHR (0.66) | TSHRPOLBKMT2AGRK2CTDSP1 | |
| SCHEMBL20116457 | 0.77 | POLB (0.78) | TSHRPOLBKMT2AGRK2CTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4013445-A | 1-(Bis-trifluoromethylphenyl)-2-oxo-pyrrolidine-4-carboxylic acid derivatives, their production and their use as plant-growth regulators and herbicides | CIBA-GEIGY CORPORATION (US) | 1977-03-22 | — | — | US | disclosed |