Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | GRK2 | P25098 | 1/20 | 0.61 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 3/20 | 0.57 |
| ▸ | CA1 | P00915 | 3/20 | 0.57 |
| ▸ | CA2 | P00918 | 3/20 | 0.57 |
| ▸ | CA4 | P22748 | 3/20 | 0.57 |
| ▸ | CA7 | P43166 | 3/20 | 0.57 |
| ▸ | CA9 | Q16790 | 3/20 | 0.57 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.57 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.57 |
| ▸ | CA6 | P23280 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12959507 | 0.87 | POLB (0.68) | TSHRKMT2APOLBGRK2CTDSP1 | |
| SCHEMBL30625999 | 0.87 | POLB (0.68) | TSHRKMT2APOLBGRK2CTDSP1 | |
| SCHEMBL26603110 | 0.87 | TSHR (0.78) | TSHRKMT2APOLBGRK2CTDSP1 | |
| SCHEMBL30626009 | 0.87 | TSHR (0.78) | TSHRKMT2APOLBGRK2CTDSP1 | |
| SCHEMBL26603140 | 0.87 | POLB (0.72) | TSHRKMT2APOLBGRK2CTDSP1 | |
| SCHEMBL1534159 | 0.85 | TSHR (0.59) | TSHRKMT2APOLBGRK2CTDSP1 | |
| SCHEMBL20676025 | 0.84 | CA12 (0.74) | TSHRKMT2APOLBGRK2CTDSP1 | |
| SCHEMBL11748147 | 0.84 | NOTUM (0.61) | TSHRKMT2APOLBGRK2CTDSP1 | |
| SCHEMBL1534237 | 0.84 | TSHR (0.57) | TSHRKMT2APOLBGRK2CTDSP1 | |
| SCHEMBL6270933 | 0.83 | CA1 (0.60) | KMT2APOLBCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |
| US-4013445-A | 1-(Bis-trifluoromethylphenyl)-2-oxo-pyrrolidine-4-carboxylic acid derivatives, their production and their use as plant-growth regulators and herbicides | CIBA-GEIGY CORPORATION (US) | 1977-03-22 | — | — | US | disclosed |