Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.49 |
| ▸ | ACACB | O00763 | 1/20 | 0.45 |
| ▸ | ACACA | Q13085 | 1/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | PTGFR | P43088 | 1/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.34 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11751086 | 0.87 | FFAR4 (0.69) | FFAR4FFAR1TBXA2RPTGFRPTGER2 | |
| SCHEMBL11749035 | 0.87 | FFAR4 (0.69) | FFAR4FFAR1TBXA2RPTGFRPTGER2 | |
| SCHEMBL11749786 | 0.87 | FFAR4 (0.47) | FFAR4FFAR1ACACBACACATBXAS1 | |
| SCHEMBL11750363 | 0.87 | FFAR4 (0.69) | FFAR4FFAR1TBXA2RPTGFRPTGER2 | |
| SCHEMBL11752741 | 0.86 | FFAR4 (0.50) | FFAR4FFAR1ACACBACACATBXAS1 | |
| SCHEMBL28351431 | 0.80 | FFAR4 (0.77) | FFAR4FFAR1FAAHTSHRALDH1A1 | |
| SCHEMBL28679768 | 0.80 | FFAR4 (0.77) | FFAR4FFAR1FAAHTSHRALDH1A1 | |
| SCHEMBL11615802 | 0.79 | FFAR4 (0.56) | FFAR4FFAR1ACACBACACATBXA2R | |
| SCHEMBL11746322 | 0.78 | FFAR4 (0.44) | FFAR4FFAR1TBXAS1TSHRALDH1A1 | |
| SCHEMBL28441741 | 0.77 | ACACB (0.56) | FFAR4FFAR1ACACBACACAFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3991087-A | RENAL VASODILATORS, HYPOTENSIVE AGENTS, ANTITHROMBOTICS | MERCK & CO., INC. (US) | 1976-11-09 | — | — | US | claimed |
| US-4059602-A | HYPOTENSIVE, VASODILATION, ANTITHROMBOSIS | MERCK & CO., INC. (US) | 1977-11-22 | — | — | US | disclosed |
| US-4059601-A | VASODILATION, HYPOTENSIVE, ANTITHROMBOSIS | MERCK & CO., INC. (US) | 1977-11-22 | — | — | US | disclosed |
| US-3991087-A | RENAL VASODILATORS, HYPOTENSIVE AGENTS, ANTITHROMBOTICS | MERCK & CO., INC. (US) | 1976-11-09 | — | — | US | disclosed |