Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.50 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | ACACA | Q13085 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 4/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.37 |
| ▸ | PTGFR | P43088 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.35 |
| ▸ | PTGER3 | P43115 | 4/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11751086 | 0.87 | FFAR4 (0.69) | FFAR4FFAR1PTGER2TBXA2RPTGFR | |
| SCHEMBL11750363 | 0.87 | FFAR4 (0.69) | FFAR4FFAR1PTGER2TBXA2RPTGFR | |
| SCHEMBL11749035 | 0.87 | FFAR4 (0.69) | FFAR4FFAR1PTGER2TBXA2RPTGFR | |
| SCHEMBL11745379 | 0.86 | FFAR4 (0.49) | FFAR4FFAR1ACACBACACAPTGER2 | |
| SCHEMBL11749786 | 0.84 | FFAR4 (0.47) | FFAR4FFAR1ACACBACACAPTGER2 | |
| SCHEMBL11746247 | 0.84 | FFAR4 (0.51) | FFAR4FFAR1ACACBACACAALOX5 | |
| SCHEMBL11620649 | 0.82 | FFAR4 (0.51) | FFAR4FFAR1ACACBACACAALOX5 | |
| SCHEMBL11787985 | 0.78 | FFAR4 (0.48) | FFAR4FFAR1ACACBACACAALOX5 | |
| SCHEMBL11516521 | 0.78 | FFAR4 (0.50) | FFAR4FFAR1ACACBACACAALOX5 | |
| SCHEMBL11514239 | 0.77 | FFAR4 (0.49) | FFAR4FFAR1ACACBACACAALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4059601-A | VASODILATION, HYPOTENSIVE, ANTITHROMBOSIS | MERCK & CO., INC. (US) | 1977-11-22 | — | — | US | disclosed |
| US-4059602-A | HYPOTENSIVE, VASODILATION, ANTITHROMBOSIS | MERCK & CO., INC. (US) | 1977-11-22 | — | — | US | disclosed |
| US-3991087-A | RENAL VASODILATORS, HYPOTENSIVE AGENTS, ANTITHROMBOTICS | MERCK & CO., INC. (US) | 1976-11-09 | — | — | US | disclosed |