Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ERCC1 | P07992 | 2/20 | 0.41 |
| ▸ | FEN1 | P39748 | 2/20 | 0.41 |
| ▸ | ERCC4 | Q92889 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | CASP6 | P55212 | 2/20 | 0.40 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | XBP1 | P17861 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11743248 | 0.84 | HSD17B10 (0.39) | POLBTDP1MAPTHSD17B10ALDH1A1 | |
| SCHEMBL11625357 | 0.82 | KDM4E (0.59) | POLBTDP1MAPTALDH1A1KDM4E | |
| SCHEMBL11750084 | 0.78 | ALDH1A1 (0.62) | POLBTDP1MAPTTSHRHSD17B10 | |
| SCHEMBL11629099 | 0.78 | MEN1 (0.48) | POLBMAPTALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL11745633 | 0.78 | KDM4E (0.48) | POLBTDP1MAPTTSHRHSD17B10 | |
| SCHEMBL11743246 | 0.78 | TYMS (0.57) | POLBTDP1MAPTHSD17B10ALDH1A1 | |
| SCHEMBL11881106 | 0.78 | ALDH1A1 (0.47) | POLBTDP1MAPTCYP1A2HSD17B10 | |
| SCHEMBL17258283 | 0.76 | ALDH1A1 (0.53) | POLBTDP1MAPTERCC1FEN1 | |
| SCHEMBL11746897 | 0.76 | KDM4E (0.52) | POLBTDP1MAPTALDH1A1KDM4E | |
| SCHEMBL6736118 | 0.76 | TYMS (0.54) | POLBTDP1MAPTCYP1A2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4007192-A | DYE INTERMEDIATES | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-02-08 | — | — | US | disclosed |