SCHEMBL11747486

SCHEMBL11747486

CCC(Oc1ccc(C(C)(C)CC)cc1C(C)(C)CC)C(=O)Nc1ccc(Cl)c(NC(=O)C(C(=O)C(C)(C)C)N2C(=O)C3CCCN3C2=O)c1

nearest known ligand 0.34

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
LMNA P02545 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
MCOLN3 Q8TDD5 1/20 0.34
EPHX2 P34913 1/20 0.32
ALDH1A1 P00352 1/20 0.32
BRAF P15056 1/20 0.30
KDR P35968 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11744322 0.90 ACKR3 (0.34) MEN1KMT2ALMNANPSR1MCOLN3
SCHEMBL11744667 0.90 TDP1 (0.33) MEN1KMT2ALMNANPSR1MCOLN3
SCHEMBL11745978 0.89 ACKR3 (0.35) MEN1KMT2AALDH1A1
SCHEMBL11748701 0.87 ALDH1A1 (0.34) MEN1KMT2ALMNANPSR1ALDH1A1
SCHEMBL11744320 0.85 ALDH1A1 (0.36) MEN1KMT2ALMNANPSR1ALDH1A1
SCHEMBL14437612 0.81 MEN1 (0.32) MEN1KMT2ALMNANPSR1MCOLN3
SCHEMBL11748078 0.81 TSHR (0.36) MEN1KMT2ALMNAALDH1A1
SCHEMBL11815112 0.81 MEN1 (0.34) MEN1KMT2ALMNANPSR1MCOLN3
SCHEMBL14037169 0.81 APOBEC3A (0.31) MEN1KMT2ALMNANPSR1MCOLN3
SCHEMBL11822785 0.81 MEN1 (0.33) MEN1KMT2ALMNANPSR1MCOLN3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4012259-A DICARBONYL METHYLENE GROUP ON A 2,5-DIOXO-1-IMIDAZOLIDINE IS A YELLOW COUPLER FUJI PHOTO FILM CO., LTD. (JA) 1977-03-15 US claimed
US-4012259-A DICARBONYL METHYLENE GROUP ON A 2,5-DIOXO-1-IMIDAZOLIDINE IS A YELLOW COUPLER FUJI PHOTO FILM CO., LTD. (JA) 1977-03-15 US disclosed