Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | NR3C1 | P04150 | 8/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 7/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | PGR | P06401 | 2/20 | 0.54 |
| ▸ | AR | P10275 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | APEX1 | P27695 | 1/20 | 0.54 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27649696 | 1.00 | KDM4E (0.61) | KDM4ENR3C1HIF1ACYP3A4NFKB1 | |
| SCHEMBL10497119 | 1.00 | KDM4E (0.61) | KDM4ENR3C1HIF1ACYP3A4NFKB1 | |
| SCHEMBL10497112 | 1.00 | KDM4E (0.61) | KDM4ENR3C1HIF1ACYP3A4NFKB1 | |
| SCHEMBL12396686 | 0.92 | NR3C1 (0.67) | KDM4ENR3C1HIF1ACYP3A4NFKB1 | |
| SCHEMBL13928662 | 0.92 | NR3C1 (0.67) | KDM4ENR3C1HIF1ACYP3A4NFKB1 | |
| SCHEMBL4221189 | 0.92 | NR3C1 (0.67) | KDM4ENR3C1HIF1ACYP3A4NFKB1 | |
| SCHEMBL27734606 | 0.92 | NR3C1 (0.67) | KDM4ENR3C1HIF1ACYP3A4NFKB1 | |
| SCHEMBL4221187 | 0.92 | NR3C1 (0.67) | KDM4ENR3C1HIF1ACYP3A4NFKB1 | |
| SCHEMBL12396656 | 0.90 | KDM4E (0.71) | KDM4ENR3C1HIF1ACYP3A4NFKB1 | |
| SCHEMBL22414814 | 0.90 | KDM4E (0.71) | KDM4ENR3C1HIF1ACYP3A4NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4024131-A | ANTIINFLAMMATORY | PLURICHEMIE ANSTALT (FL) | 1977-05-17 | — | — | US | disclosed |