Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | TP53 | P04637 | 5/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 8/20 | 0.39 |
| ▸ | NPC1 | O15118 | 7/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 5/20 | 0.39 |
| ▸ | JAK2 | O60674 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11747270 | 0.92 | TP53 (0.45) | ALDH1A1TP53NR1I2KMT2AMEN1 | |
| SCHEMBL11798882 | 0.89 | TP53 (0.42) | ALDH1A1TP53NR1I2KMT2AMEN1 | |
| SCHEMBL11750233 | 0.86 | TP53 (0.48) | ALDH1A1TP53NR1I2KMT2AMEN1 | |
| SCHEMBL11744133 | 0.82 | ALDH1A1 (0.54) | ALDH1A1TP53KMT2AMEN1TDP1 | |
| SCHEMBL11385609 | 0.82 | TP53 (0.58) | ALDH1A1TP53NR1I2KMT2AMEN1 | |
| SCHEMBL11747345 | 0.81 | TP53 (0.41) | ALDH1A1TP53NR1I2KMT2AMEN1 | |
| SCHEMBL11746091 | 0.81 | TP53 (0.46) | ALDH1A1TP53NR1I2KMT2AMEN1 | |
| SCHEMBL11744292 | 0.81 | TP53 (0.46) | ALDH1A1TP53NR1I2KMT2AMEN1 | |
| SCHEMBL11748862 | 0.80 | TDP1 (0.42) | ALDH1A1TP53NR1I2KMT2AMEN1 | |
| SCHEMBL11745389 | 0.79 | TDP1 (0.50) | ALDH1A1TP53NR1I2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4053297-A | COMPRISING AN ANILIDE DERIVATIVE AND AN N-SUBSTITUTED 2,2-DICHLOROACETAMIDE | VELSICOL CHEMICAL CORPORATION (US) | 1977-10-11 | — | — | US | disclosed |