Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.37 |
| ▸ | PGR | P06401 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.36 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.35 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.32 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11745681 | 0.94 | LMNA (0.40) | LMNANR1I2CYP3A4NR3C1PGR | |
| SCHEMBL11749436 | 0.94 | LMNA (0.40) | LMNANR1I2CYP3A4NR3C1PGR | |
| SCHEMBL11746766 | 0.84 | CYP19A1 (0.39) | LMNANR1I2CYP3A4NR3C1PGR | |
| SCHEMBL11745689 | 0.81 | LMNA (0.39) | LMNANR1I2CYP3A4NR3C1PGR | |
| SCHEMBL11744273 | 0.75 | LMNA (0.35) | LMNANR1I2CYP3A4NR3C1PGR | |
| SCHEMBL11744287 | 0.75 | LMNA (0.35) | LMNANR1I2CYP3A4NR3C1PGR | |
| SCHEMBL11745349 | 0.75 | LMNA (0.35) | LMNANR1I2CYP3A4NR3C1PGR | |
| SCHEMBL11746771 | 0.72 | CYP19A1 (0.37) | LMNANR1I2CYP3A4NR3C1PGR | |
| SCHEMBL11747490 | 0.72 | LMNA (0.32) | LMNANR1I2CYP3A4NR3C1PGR | |
| SCHEMBL11598171 | 0.70 | LMNA (0.40) | LMNANR1I2CYP3A4NR3C1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4058539-A | 4,6,8(14)-Triene steroids | STEELE CHEMICALS CO. LTD. (CA) | 1977-11-15 | — | — | US | disclosed |