Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 5/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | GLP1R | P43220 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11677248 | 0.83 | ATM (0.34) | PGK1TLR7ATMPOLBDPP4 | |
| SCHEMBL11674497 | 0.81 | POLB (0.35) | POLBTDP1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL11751563 | 0.80 | PGK1 (0.46) | PGK1TLR7ATMPOLBGAA | |
| SCHEMBL11675190 | 0.79 | PGK1 (0.48) | PGK1TLR7ATMGAATDP1 | |
| SCHEMBL11676388 | 0.77 | TLR7 (0.47) | PGK1TLR7GAATDP1MAPT | |
| SCHEMBL11749770 | 0.76 | PGK1 (0.50) | PGK1TLR7ATMGAATDP1 | |
| SCHEMBL11676597 | 0.75 | PGK1 (0.42) | PGK1TLR7ATMGAATDP1 | |
| SCHEMBL11861851 | 0.74 | POLB (0.33) | POLB | |
| SCHEMBL3054833 | 0.71 | PGK1 (0.41) | PGK1TLR7POLBGAAMAPT | |
| SCHEMBL11750054 | 0.71 | PGK1 (0.44) | PGK1ATMPOLBGAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055411-A | 5-NITRO-PYRIMIDINES | CIBA-GEIGY CORPORATION (US) | 1977-10-25 | — | — | US | disclosed |
| US-3948914-A | PLANT GROWTH REGULATORS | CIBA-GEIGY CORPORATION (US) | 1976-04-06 | — | — | US | disclosed |