Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HTR2A | P28223 | 2/20 | 0.50 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.50 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.48 |
| ▸ | SRC | P12931 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11743621 | 0.92 | CHRNA7 (0.45) | MAPTHTR2ASCN9ACHRNA7KMT2A | |
| SCHEMBL11749818 | 0.92 | CHRNA7 (0.45) | MAPTHTR2ASCN9ACHRNA7KMT2A | |
| SCHEMBL11744352 | 0.84 | MAPT (0.69) | MAPTSCN9AKMT2AMEN1NPSR1 | |
| SCHEMBL11744818 | 0.83 | MAPT (0.50) | MAPTSCN9AKMT2AMEN1NPSR1 | |
| SCHEMBL11747226 | 0.81 | MAPT (0.48) | MAPTHTR2ASCN9ACHRNA7KMT2A | |
| SCHEMBL11742877 | 0.80 | MEN1 (0.63) | MAPTKMT2AMEN1NPSR1TP53 | |
| SCHEMBL11742574 | 0.80 | ALDH1A1 (0.43) | MAPTSCN9AKMT2AMEN1NPSR1 | |
| SCHEMBL11748212 | 0.79 | SCN9A (0.48) | MAPTSCN9AKMT2AMEN1NPSR1 | |
| Hydrochloric Acid SCHEMBL9695711 | 0.78 | KDM4E (0.47) | KMT2AMEN1TP53KDM4EALDH1A1 | |
| SCHEMBL14249540 | 0.78 | SRC (0.60) | MAPTHTR2ASCN9ACHRNA7KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4008232-A | ANTIINFLAMMATORY | ELI LILLY AND COMPANY (US) | 1977-02-15 | — | — | US | disclosed |
| US-3979516-A | Anti-inflammatory 3-amino-5,6-diaryl-1,2,4-triazines | ELI LILLY AND COMPANY (US) | 1976-09-07 | — | — | US | disclosed |
| US-3948894-A | ANTIINFLAMMATORY | ELI LILLY AND COMPANY (US) | 1976-04-06 | — | — | US | disclosed |