Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 5/20 | 0.47 |
| ▸ | RXRA | P19793 | 2/20 | 0.44 |
| ▸ | RXRB | P28702 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | C1R | P00736 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11747694 | 0.87 | NR4A2 (0.61) | NPC1RAB9ASMN1; SMN2TP53HPGD | |
| SCHEMBL11755172 | 0.87 | NR4A2 (0.58) | NPC1RAB9ASMN1; SMN2TP53HPGD | |
| SCHEMBL11753246 | 0.81 | NR4A2 (0.44) | NPC1RAB9ASMN1; SMN2TP53HPGD | |
| SCHEMBL11752837 | 0.78 | NR4A2 (0.50) | NPC1RAB9ASMN1; SMN2TP53HPGD | |
| SCHEMBL11749400 | 0.78 | NR4A2 (0.46) | NPC1RAB9ASMN1; SMN2TP53HPGD | |
| SCHEMBL11755732 | 0.78 | ELANE (0.39) | NPC1RAB9ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL11748293 | 0.75 | ALDH1A1 (0.60) | NPC1RAB9ASMN1; SMN2HPGDNR4A2 | |
| SCHEMBL11752486 | 0.74 | ALDH1A1 (0.53) | NPC1RAB9ASMN1; SMN2TP53HPGD | |
| SCHEMBL11752200 | 0.70 | ALDH1A1 (0.46) | NPC1RAB9ASMN1; SMN2TP53HPGD | |
| SCHEMBL11754130 | 0.70 | NR4A2 (0.56) | NPC1RAB9ASMN1; SMN2TP53HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4051250-A | OXAZOLE, THIAZOLE | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-09-27 | — | — | US | disclosed |
| US-3933840-A | ANTIPHLOGISTIC | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1976-01-20 | — | — | US | disclosed |