Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 6/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | LAP3 | P28838 | 2/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15355365 | 1.00 | TSHR (0.47) | TSHRHCAR2ATMALDH1A1HPGD | |
| SCHEMBL11748242 | 1.00 | TSHR (0.47) | TSHRHCAR2ATMALDH1A1HPGD | |
| SCHEMBL11748250 | 0.92 | HCAR2 (0.52) | TSHRHCAR2ATMALDH1A1HPGD | |
| SCHEMBL11746726 | 0.83 | TSHR (0.70) | TSHRALDH1A1HPGD | |
| SCHEMBL429885 | 0.81 | TSHR (0.67) | TSHRHCAR2ATMALDH1A1HPGD | |
| SCHEMBL317107 | 0.81 | TSHR (0.67) | TSHRHCAR2ATMALDH1A1HPGD | |
| SCHEMBL317108 | 0.81 | TSHR (0.67) | TSHRHCAR2ATMALDH1A1HPGD | |
| SCHEMBL9576235 | 0.81 | TSHR (0.45) | TSHRHCAR2ATMALDH1A1HPGD | |
| SCHEMBL11747186 | 0.80 | MAPT (0.46) | TSHRHCAR2ATMALDH1A1HPGD | |
| SCHEMBL28367450 | 0.80 | MAPT (0.46) | TSHRHCAR2ATMALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4048130-A | COPOLYMERIZATION, UNSATURATED ACIDS | LONZA LTD. (CH) | 1977-09-13 | — | — | US | disclosed |