Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11583058 | 0.84 | GAA (0.34) | GAAKMT2APOLBFASN | |
| SCHEMBL4363225 | 0.80 | ADORA1 (0.54) | GAAADORA1KMT2AATMMAPT | |
| SCHEMBL29733018 | 0.77 | EGFR (0.39) | GAAKMT2AL3MBTL1MAPTMEN1 | |
| SCHEMBL24553999 | 0.77 | EGFR (0.39) | GAAKMT2AL3MBTL1MAPTMEN1 | |
| SCHEMBL13907870 | 0.77 | KMT2A (0.40) | ADORA1KMT2AATMMAPTMEN1 | |
| SCHEMBL11749738 | 0.75 | GAA (0.40) | TSHRGAAKMT2AALOX15ATM | |
| SCHEMBL13907881 | 0.75 | NPC1 (0.37) | TSHRADORA1KMT2AATMMAPT | |
| SCHEMBL8985172 | 0.74 | KMT2A (0.49) | TSHRGAAKMT2AALOX15L3MBTL1 | |
| SCHEMBL13907874 | 0.74 | CACNA1H (0.37) | ADORA1KMT2AATMMAPTMEN1 | |
| SCHEMBL6311638 | 0.73 | KMT2A (0.62) | GAAKMT2AATMMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009034029-A2 | 1-SUBSTITUTED 4-HETEROCYCLYLPIPERIDINES FOR USE AS CGRP ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-03-19 | — | — | WO | disclosed |
| US-4051099-A | ISOINDOLES | CIBA-GEIGY CORPORATION (US) | 1977-09-27 | — | — | US | disclosed |
| US-3994899-A | METHINE | CIBA-GEIGY CORPORATION (US) | 1976-11-30 | — | — | US | disclosed |