Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.49 |
| ▸ | POLB | P06746 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 7/20 | 0.45 |
| ▸ | NPC1 | O15118 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8985181 | 0.87 | KMT2A (0.66) | KMT2APOLBRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL31516298 | 0.87 | KMT2A (0.66) | KMT2APOLBRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL30401567 | 0.81 | IDO1 (0.45) | POLBRAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL11339364 | 0.81 | TDP1 (0.47) | KMT2APOLBRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL3391736 | 0.81 | GRIN1 (0.43) | KMT2AMEN1EGFR | |
| SCHEMBL12940748 | 0.81 | CSNK2A1 (0.45) | KMT2APOLBRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL29014490 | 0.81 | IDO1 (0.45) | POLBRAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL12596890 | 0.81 | EGFR (0.42) | KMT2APOLBRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL10833211 | 0.80 | ALDH1A1 (0.46) | KMT2APOLBRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL6311638 | 0.80 | KMT2A (0.62) | KMT2APOLBRAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110872288-A | Method for synthesizing benzimidazole [1,2-a ] quinoline compound | 浙江工业大学 | 2020-03-10 | — | — | CN | disclosed |
| EP-0612732-B1 | Process for the production of (un)substituted 2-(cyanomethyl)benzimidazole | HOECHST AG (DE) | 1996-07-17 | — | — | EP | disclosed |
| US-5510494-A | REACTING AN ORTHO-PHENYLENEDIAMINE WITH A CYANOACETIC ESTER IN A HALOGEN-FREE INERT SOLVENT WITHOUT ADDING AN AROMATIC SULFONIC ACID AS CATALYST | HOECHST AG (DE) | 1996-04-23 | — | — | US | disclosed |
| EP-0612732-A1 | Process for the production of (un)substituted 2-(cyanomethyl)benzimidazole | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-08-31 | — | — | EP | disclosed |
| US-4268668-A | FOR WOOL AND POLYAMIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1981-05-19 | — | — | US | disclosed |
| US-4051099-A | ISOINDOLES | CIBA-GEIGY CORPORATION (US) | 1977-09-27 | — | — | US | disclosed |