Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | XBP1 | P17861 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 12/20 | 0.50 |
| ▸ | ACHE | P22303 | 3/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.40 |
| ▸ | GCGR | P47871 | 1/20 | 0.40 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.40 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11750667 | 1.00 | KDM4E (0.54) | KDM4ELMNAMAPTXBP1MAPK1 | |
| SCHEMBL11747493 | 0.92 | PTGS2 (0.49) | KDM4ELMNAMAPTXBP1MAPK1 | |
| SCHEMBL11755436 | 0.92 | MAPT (0.62) | KDM4ELMNAMAPTXBP1MAPK1 | |
| SCHEMBL11753884 | 0.85 | MAPT (0.56) | KDM4ELMNAMAPTXBP1MAPK1 | |
| SCHEMBL11751111 | 0.85 | MAPT (0.56) | KDM4ELMNAMAPTXBP1MAPK1 | |
| SCHEMBL11752179 | 0.85 | PTGS2 (0.53) | KDM4EMAPTPTGS2PTGS1 | |
| SCHEMBL11756102 | 0.85 | PTGS2 (0.53) | KDM4EMAPTPTGS2PTGS1 | |
| SCHEMBL11750931 | 0.84 | MAPT (0.54) | KDM4ELMNAMAPTXBP1MAPK1 | |
| SCHEMBL11755381 | 0.84 | KDM4E (0.54) | KDM4ELMNAMAPTXBP1MAPK1 | |
| SCHEMBL11754200 | 0.84 | MAPT (0.54) | KDM4ELMNAMAPTXBP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4051250-A | OXAZOLE, THIAZOLE | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-09-27 | — | — | US | disclosed |
| US-3933840-A | ANTIPHLOGISTIC | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1976-01-20 | — | — | US | disclosed |