Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SETD7 | Q8WTS6 | 7/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.47 |
| ▸ | HTR1A | P08908 | 3/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.47 |
| ▸ | DRD1 | P21728 | 3/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.47 |
| ▸ | DRD3 | P35462 | 3/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11753343 | 0.88 | SETD7 (0.47) | SETD7CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL11733579 | 0.88 | SETD7 (0.64) | SETD7CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL11727471 | 0.84 | SETD7 (0.36) | SETD7CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL11753249 | 0.78 | SETD7 (0.55) | SETD7CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL11737418 | 0.74 | SETD7 (0.45) | SETD7CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL11733673 | 0.74 | SETD7 (0.48) | SETD7CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL11478334 | 0.74 | SETD7 (0.50) | SETD7CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL11464514 | 0.74 | SETD7 (0.50) | SETD7CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL11683965 | 0.73 | SETD7 (0.65) | SETD7CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL11733293 | 0.71 | SETD7 (0.34) | SETD7OPRM1DRD2HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4031223-A | ANTIEXTRAPYRAMIDAL, ANTIPSYCHOTIC, ENANTIOMERS, TRANQUILIZERS, ANTICHOLINERGIC | MERCK & CO., INC. (US) | 1977-06-21 | — | — | US | disclosed |