Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.53 |
| ▸ | ICMT | O60725 | 2/20 | 0.52 |
| ▸ | ALB | P02768 | 2/20 | 0.52 |
| ▸ | THRA | P10827 | 3/20 | 0.50 |
| ▸ | THRB | P10828 | 3/20 | 0.50 |
| ▸ | CES2 | O00748 | 2/20 | 0.50 |
| ▸ | CES1 | P23141 | 2/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | NAAA | Q02083 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11749346 | 1.00 | MAPT (0.53) | MAPTKDM4EALDH1A1AGTR1ICMT | |
| SCHEMBL11745805 | 1.00 | MAPT (0.53) | MAPTKDM4EALDH1A1AGTR1ICMT | |
| SCHEMBL11754086 | 1.00 | MAPT (0.53) | MAPTKDM4EALDH1A1AGTR1ICMT | |
| SCHEMBL11749501 | 0.98 | KDM4E (0.54) | MAPTKDM4EALDH1A1AGTR1ICMT | |
| SCHEMBL11749642 | 0.93 | KDM4E (0.56) | MAPTKDM4EALDH1A1AGTR1THRA | |
| SCHEMBL4097123 | 0.86 | MAPT (0.59) | MAPTKDM4EALDH1A1AGTR1CES2 | |
| SCHEMBL11749468 | 0.84 | KCNH2 (0.51) | THRATHRBKCNH2 | |
| SCHEMBL11745793 | 0.84 | KCNH2 (0.51) | THRATHRBKCNH2 | |
| SCHEMBL11749359 | 0.84 | THRA (0.51) | ALDH1A1THRATHRBNPC1RAB9A | |
| SCHEMBL11749967 | 0.84 | THRA (0.51) | ALDH1A1THRATHRBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4048034-A | Photopolymerization using an alpha-aminoacetophenone | UOP INC. (US) | 1977-09-13 | — | — | US | disclosed |