Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.70 |
| ▸ | POLB | P06746 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.70 |
| ▸ | MEN1 | O00255 | 4/20 | 0.70 |
| ▸ | RAB9A | P51151 | 6/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5439226 | 0.83 | KDM4E (0.75) | NPC1POLBKMT2AMEN1RAB9A | |
| SCHEMBL4548097 | 0.82 | ABCG2 (0.65) | NPC1POLBKMT2AMEN1RAB9A | |
| SCHEMBL29124110 | 0.81 | NPC1 (1.00) | NPC1POLBKMT2AMEN1RAB9A | |
| SCHEMBL11291466 | 0.81 | NPC1 (0.79) | NPC1POLBKMT2AMEN1RAB9A | |
| SCHEMBL6396790 | 0.79 | RAB9A (0.76) | NPC1POLBKMT2AMEN1RAB9A | |
| SCHEMBL2114596 | 0.79 | RAB9A (1.00) | NPC1POLBKMT2AMEN1RAB9A | |
| SCHEMBL30273063 | 0.79 | RAB9A (1.00) | NPC1POLBKMT2AMEN1RAB9A | |
| SCHEMBL30273064 | 0.79 | RAB9A (1.00) | NPC1POLBKMT2AMEN1RAB9A | |
| SCHEMBL1600148 | 0.79 | NPC1 (0.61) | NPC1POLBKMT2AMEN1RAB9A | |
| SCHEMBL13451640 | 0.78 | MEN1 (0.73) | NPC1POLBKMT2AMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4003875-A | ULTRAVIOLET ABSORBERS | CIBA-GEIGY CORPORATION (US) | 1977-01-18 | — | — | US | claimed |
| US-4003875-A | ULTRAVIOLET ABSORBERS | CIBA-GEIGY CORPORATION (US) | 1977-01-18 | — | — | US | disclosed |