SCHEMBL11752158

SCHEMBL11752158

CCC(=O)Nc1cccc(NC(=O)C2CC2)c1

nearest known ligand 0.66

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.66
NR4A1 P22736 1/20 0.66
RAB9A P51151 1/20 0.66
SMN1; SMN2 Q16637 3/20 0.62
GAA P10253 3/20 0.59
LMNA P02545 3/20 0.59
KMT2A Q03164 3/20 0.59
MEN1 O00255 2/20 0.59
HTT P42858 2/20 0.59
NPSR1 Q6W5P4 1/20 0.59
USP2 O75604 1/20 0.59
HPGD P15428 1/20 0.59
ALDH1A1 P00352 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11752877 0.94 SMN1; SMN2 (0.68) POLBNR4A1RAB9ASMN1; SMN2GAA
SCHEMBL10970617 0.86 RAB9A (0.85) POLBNR4A1RAB9ASMN1; SMN2GAA
SCHEMBL12847284 0.83 SMN1; SMN2 (0.65) SMN1; SMN2GAALMNAKMT2AMEN1
SCHEMBL10294106 0.83 GAA (0.57) SMN1; SMN2GAALMNAKMT2AMEN1
SCHEMBL18774005 0.83 SMN1; SMN2 (0.89) SMN1; SMN2GAALMNAKMT2AMEN1
SCHEMBL11869674 0.82 SMN1; SMN2 (0.57) SMN1; SMN2GAALMNAKMT2AMEN1
SCHEMBL19327634 0.80 GLA (0.62) POLBRAB9ASMN1; SMN2GAALMNA
SCHEMBL19327623 0.80 GLA (0.62) POLBRAB9ASMN1; SMN2GAALMNA
SCHEMBL19327620 0.80 GLA (0.62) POLBRAB9ASMN1; SMN2GAALMNA
SCHEMBL19327773 0.80 GLA (0.62) POLBRAB9ASMN1; SMN2GAALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4028093-A Meta-bis anilide derivatives and their utility as herbicides STAUFFER CHEMICAL COMPANY (US) 1977-06-07 US disclosed
US-3941581-A Meta-bis anilide derivatives and their utility as herbicides STAUFFER CHEMICAL COMPANY (US) 1976-03-02 US disclosed
US-3937729-A META-BIS ANILIDE DERIVATIVES AND THEIR UTILITY AS HERBICIDES STAUFFER CHEMICAL COMPANY (US) 1976-02-10 US disclosed