Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 7/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 4/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11749780 | 0.96 | SMN1; SMN2 (0.49) | SMN1; SMN2ALDH1A1LMNAHPGDAKR1C3 | |
| SCHEMBL11754433 | 0.93 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1LMNAHPGDAKR1C3 | |
| SCHEMBL11746093 | 0.89 | ALDH1A1 (0.47) | LTA4HSMN1; SMN2ALDH1A1LMNAHPGD | |
| SCHEMBL11750531 | 0.86 | NPC1 (0.44) | SMN1; SMN2ALDH1A1LMNAPPARGMAPT | |
| SCHEMBL11752197 | 0.84 | MAPT (0.50) | SMN1; SMN2ALDH1A1LMNAHPGDMAPT | |
| SCHEMBL11566109 | 0.84 | PPARG (0.57) | PPARGPPARAKMT2A | |
| SCHEMBL11748490 | 0.82 | NPC1 (0.46) | SMN1; SMN2ALDH1A1LMNAPPARGMAPT | |
| SCHEMBL11727460 | 0.82 | ALDH1A1 (0.52) | LTA4HSMN1; SMN2ALDH1A1LMNAHPGD | |
| SCHEMBL11752894 | 0.81 | ALDH1A1 (0.47) | SMN1; SMN2ALDH1A1LMNAHPGDMAPT | |
| SCHEMBL11751032 | 0.81 | MAPT (0.44) | LTA4HSMN1; SMN2ALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4053626-A | CHOLESTEROL LEVEL-LOWERING PHENOXYACETIC ACIDS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-10-11 | — | — | US | disclosed |
| US-3992386-A | 4(Quinolyl)phenoxy alkanoic acid derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1976-11-16 | — | — | US | disclosed |