Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 6/20 | 0.71 |
| ▸ | RAB9A | P51151 | 6/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.63 |
| ▸ | MAPT | P10636 | 4/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | USP2 | O75604 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.51 |
| ▸ | RARA | P10276 | 1/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.49 |
| ▸ | RELA | Q04206 | 3/20 | 0.49 |
| ▸ | STAT3 | P40763 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11757127 | 1.00 | RARB (0.71) | RARBRAB9ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL11754942 | 0.98 | RARB (0.68) | RARBRAB9ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL27311225 | 0.97 | RARB (0.70) | RARBRAB9ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL27344065 | 0.97 | RARB (0.70) | RARBRAB9ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL27314694 | 0.97 | RARB (0.70) | RARBRAB9ASMN1; SMN2MAPTMEN1 | |
| Water SCHEMBL27285934 | 0.95 | RARB (0.68) | RARBRAB9ASMN1; SMN2MAPTMEN1 | |
| Water SCHEMBL27285888 | 0.95 | RARB (0.68) | RARBRAB9ASMN1; SMN2MAPTMEN1 | |
| Water SCHEMBL27285890 | 0.95 | RARB (0.68) | RARBRAB9ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL9560137 | 0.95 | RARB (0.68) | RARBRAB9ASMN1; SMN2MAPTMEN1 | |
| Acetic Acid SCHEMBL9271487 | 0.93 | RARB (0.75) | RARBRAB9ASMN1; SMN2MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4062798-A | NEMATIC CRYSTALS | HOFFMANN-LA ROCHE INC. (US) | 1977-12-13 | — | — | US | disclosed |