SCHEMBL9560137

SCHEMBL9560137

CCCCCc1cnc(-c2ccccc2)nc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 2/20 0.68
RAB9A P51151 5/20 0.59
SMN1; SMN2 Q16637 4/20 0.59
MAPT P10636 3/20 0.59
KDM4E B2RXH2 1/20 0.59
MEN1 O00255 1/20 0.59
USP2 O75604 1/20 0.59
ALDH1A1 P00352 1/20 0.59
GAA P10253 1/20 0.59
HPGD P15428 1/20 0.59
KMT2A Q03164 1/20 0.59
HSD17B10 Q99714 1/20 0.59
HSD11B1 P28845 2/20 0.51
NPC1 O15118 3/20 0.49
NFKB1 P19838 2/20 0.49
NFKB2 Q00653 2/20 0.49
RELA Q04206 2/20 0.49
GPR84 Q9NQS5 1/20 0.49
L3MBTL1 Q9Y468 2/20 0.47
TDP1 Q9NUW8 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27311225 0.98 RARB (0.70) RARBRAB9ASMN1; SMN2MAPTKDM4E
SCHEMBL27344065 0.98 RARB (0.70) RARBRAB9ASMN1; SMN2MAPTKDM4E
SCHEMBL27314694 0.98 RARB (0.70) RARBRAB9ASMN1; SMN2MAPTKDM4E
SCHEMBL11754942 0.97 RARB (0.68) RARBRAB9ASMN1; SMN2MAPTKDM4E
Water SCHEMBL27285934 0.97 RARB (0.68) RARBRAB9ASMN1; SMN2MAPTKDM4E
Water SCHEMBL27285890 0.97 RARB (0.68) RARBRAB9ASMN1; SMN2MAPTKDM4E
Water SCHEMBL27285888 0.97 RARB (0.68) RARBRAB9ASMN1; SMN2MAPTKDM4E
SCHEMBL11753138 0.95 RARB (0.71) RARBRAB9ASMN1; SMN2MAPTKDM4E
SCHEMBL11757127 0.95 RARB (0.71) RARBRAB9ASMN1; SMN2MAPTKDM4E
Propanol SCHEMBL9797518 0.92 RARB (0.68) RARBRAB9ASMN1; SMN2MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-5255278-A None JP disclosed
US-8993754-B2 Iridium complex and light emitting material formed from same NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2015-03-31 US disclosed
US-20120208999-A1 IRIDIUM COMPLEX AND LIGHT EMITTING MATERIAL FORMED FROM SAME NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2012-08-16 US disclosed
JP-H05255278-A PYRIMIDINE DERIVATIVE CITIZEN WATCH CO LTD 1993-10-05 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120208999-A1 IRIDIUM COMPLEX AND LIGHT EMITTING MATERIAL FORMED FROM SAME LUC7L2, CRY1, INTS9 RARB 3014/4885RAB9A 1983/4885SMN1; SMN2 1633/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.