Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 3/20 | 0.43 |
| ▸ | RXRB | P28702 | 3/20 | 0.43 |
| ▸ | RXRG | P48443 | 3/20 | 0.43 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | VCP | P55072 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11749255 | 1.00 | NR4A2 (0.43) | NR4A2RXRARXRBRXRGCNR1 | |
| SCHEMBL11753348 | 0.95 | NR4A2 (0.47) | NR4A2RXRARXRBRXRGKDM4E | |
| SCHEMBL11752390 | 0.91 | RXRA (0.48) | NR4A2RXRARXRBRXRGCNR1 | |
| SCHEMBL11752368 | 0.88 | NR4A2 (0.59) | NR4A2RXRARXRBRXRGKDM4E | |
| SCHEMBL11752294 | 0.88 | NR4A2 (0.59) | NR4A2RXRARXRBRXRGKDM4E | |
| SCHEMBL11745479 | 0.84 | RXRA (0.57) | NR4A2RXRARXRBRXRGKDM4E | |
| SCHEMBL11754360 | 0.84 | RXRA (0.57) | NR4A2RXRARXRBRXRGKDM4E | |
| SCHEMBL11753438 | 0.83 | NR4A2 (0.41) | NR4A2RXRARXRBRXRGCNR1 | |
| SCHEMBL11756164 | 0.83 | NR4A2 (0.41) | NR4A2RXRARXRBRXRGCNR1 | |
| SCHEMBL11749112 | 0.83 | RXRA (0.46) | NR4A2RXRARXRBRXRGCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4051250-A | OXAZOLE, THIAZOLE | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-09-27 | — | — | US | disclosed |
| US-3933840-A | ANTIPHLOGISTIC | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1976-01-20 | — | — | US | disclosed |